Dr. Prem R. Meena

About Research 

Antimicrobial resistance (AMR) represents a critical and escalating challenge to global health as many antibiotics are losing efficacy against emerging multidrug-resistant pathogens. Resistance arises naturally through genetic mutations and horizontal gene transfer, with its spread accelerated by the overuse of antibiotics in humans, animals, and agriculture. Environmental dissemination further connects AMR across humans, animals, and ecosystems, emphasizing the importance of a One-Health framework to address this complex issue.

Our laboratory investigates the molecular mechanisms underlying the evolution and spread of antibiotic resistance. We focus on bacterial virulence and fitness factors, including biofilm formation, while also developing innovative therapeutic strategies to counteract resistant infections. By integrating genomic, transcriptomic, and phenotypic analyses, we aim to deepen the understanding of AMR dynamics and contribute to the development of effective interventions against global infectious disease threats.

Research Areas:

• Microbial Genomics of Multidrug-Resistant Pathogens in the One Health Context
• Microbial Pathogenesis and Infectious Disease
• Microbiome and Metagenomics

Google Scholar—https://scholar.google.com/citations?user=J5CUadYAAAAJ&hl=en
ORCID iD—https://orcid.org/0000-0001-7623-1065

Research Experience 

• Post-Doctoral Researcher, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University-Hadassah Medical School, Jerusalem, Israel (2025) 
• Research Associate, Jawaharlal Nehru University, New Delhi, India (2023)
• Research Associate, CSIR–National Institute of Science Communication and Policy Research (CSIR–NIScPR), New Delhi, India (2024)
• Research Scientist, Seloi Healthcare Pvt. Ltd, Mumbai, Maharashtra, India (2021) 
• Ph.D. Research Scholar, Central University of Rajasthan, Ajmer, India (2021)
• Senior Research Fellow, CSIR-Institute of Genomics and Integrative Biology (CSIR–IGIB), New Delhi, India (2015)

Teaching Experience

• Assistant Professor (July, 2025–Cont.), Department of Biotechnology, Delhi Technological University, New Delhi, India 
• Assistant Professor (2022-2023), Department of Biomedical Engineering, Central University of Rajasthan, Ajmer, India 

• The Society of Biological Chemists (India)
• Applied Microbiology International
• Indian Science Congress, India

Selected Publication

• Priyanka, Meena PR, Mishra P, Jha AK, Duggirala KS, Dhanokar A, Kumar A, D Raj, Rana A, Singh AP (2024). A One Health Exploration of Antimicrobial Resistance in E. coli Originated from Urban and Rural Lake Ecosystems. Lett. in Appl. Microbiol. 
• Meena PR, Priyanka P, Singh AP (2023). Extraintestinal Pathogenic E. coli (ExPEC) Reservoirs and Antibiotics Resistance Trends: A One-Health Surveillance for Risk Analysis from “Farm-to-Fork”. Letters in Applied Microbiology, 76, 1-12. 
• Priyanka, Meena PR, Raj D, Rana A, Dhanokar A, Duggirala KS, Singh AP (2023). Urinary tract infection and sepsis causing potential of multidrug-resistant Extraintestinal pathogenic E. coli isolated from plant-origin foods. International Journal of Food Microbiology, 380. 
• Meena PR, Yadav P, Rana A, Raj D, Singh AP (2022). Alarming level of single or multidrug resistance in poultry environments-associated Extraintestinal pathogenic Escherichia coli pathotypes with potential to affect the One Health. Environ Microbiol. Repor. 14(3), 400-411. 
• Dar MA, Chanwala J, Meena PR, Singh AP, Kaushik G (2022). Biodegradation of malathion by Micrococcus sp. strain MAGK3: kinetics and degradation fragments. Archives of Microbiology. 204(8):482. 
• Meena PR, Yadav P, Hemlata H, Tejavath KK, Singh AP (2020). Poultry-origin extraintestinal Escherichia coli strains carrying the traits associated with urinary tract infection, sepsis, meningitis, and avian colibacillosis in India. J Appl Microbiol. 130(6):2087-2101. 
• Hemlata, Meena PR, Singh AP, Tejavath KK (2021). Assessment of antioxidant, cytotoxic, anti-proliferative, and anti-bacterial activities using the bioinspired silver nanoparticles via Cucumis prophetarum fruit extract. Inorganic and Nano-metal Chemistry.
• Priyanka, Meena PR, Meghwanshi KK, Rana A, Singh AP (2021). Leafy greens as a potential source of multidrug-resistant diarrheagenic Escherichia coli and Salmonella. Microbiology. 167(6). 
• Hemlata, Meena PR, Singh, AP, Tejavath, KK (2020). Biosynthesis of Silver Nanoparticles Using Cucumis prophetarum Aqueous Leaf Extract and Their Antibacterial and Antiproliferative Activity Against Cancer Cell Lines. A.C.S. omega, 5(10), 5520-5528. 
• Meena PR, Vashishth A, Priyanka, Singh AP (2020). Pandemic COVID-19 Emerging Global Concern: An Overview to Understand the Potential of Ca⁺² in Pathogenesis and Advance Therapeutic Strategy on its Outbreak. J Microb Biochem Technol. 12. 3: 433. 
• Meena PR, Monu, Meena LS (2016). Fibronectin binding protein and Ca²⁺ play an access key role to mediate pathogenesis in Mycobacterium tuberculosis: An overview. Biotechnol Appl Biochem. 63(6):820-826. 

• Shivam Mishra, Arijit Pal, Neha Singh, Poonam Sharma, Prem Raj Meena, Vishal Srivastava, Sheetal Bandhu, Vaagmi Aggarwal, Bimal Das, Tapan K Chaudhuri (2025). The Future of Biofilm Treatment: Challenges and Opportunities. Bentham Science Publishers

Awards and Fellowships

• Post-Doctoral Researcher, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University-Hadassah Medical School, Jerusalem, Israel 
• NOS, Post-Doc Fellowship, Govt. of India, Rutgers University, New Jersey, United States
• DBT-RA, Department of Biotechnology, Govt. of India, Jawaharlal Nehru University, New Delhi, India
• National Fellowship for Higher Education, Government of India, India
• Graduate Aptitude Test in Engineering (GATE) (Life Sciences)
• Council of Scientific & Industrial Research (CSIR)-NET-JRF (Life Sciences)

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Reviewer of Peer-reviewed Journals 

• Frontiers in Microbiology 
• Antimicrobials, Resistance and Chemotherapy 
• Journal of Microbial & Biochemical Technology
• Health Science Report

• Participated in Faculty Development Program on “Course File Preparation and Question Paper Setting based on OBE,” organized by Delhi Technological University from 13th -to 17th October, 2025
• Symposium-cum-workshop on “Ancient Roots, Modern Tools: IKS as the Foundation for Future Biotechnology,” Department of Biotechnology, Delhi Technological University (DTU), 2025.
• Antimicrobial Chemotherapy Conference 2024, organized by GARDP and British Society for Antimicrobial Chemotherapy, Geneva, Switzerland
• AMI International Conference organized by the Association of Microbiology
• International Conference on Molecular Basis of Diseases and Therapeutics (ICMBDT-2019) organized by Central University of Rajasthan, Ajmer.
• National workshop on “Advanced Techniques in Nanoscience and Technology” at INST Mohali, December 2017, 2018, and 2019)
• Workshop on “National workshop on foldscope and symposium on Applied Microbiology,” at Department of Chemistry, Manipal University, India
• National Workshop on Internet Security, Central University of Rajasthan, Ajmer.
• National workshop on “Genomics, Proteomics, and Bioinformatics" (D.A.V., Indore)