PROFILE

Prof. Gurudutta Gangenahalli is an accomplished defence scientist and academician. Prof. Gurudutta has had an illustrious research career spanning over 40 years. Before joining the department, he served at the prestigious Netaji Subhas University of Technology (NSUT) as a Professor Emeritus. Prof. Gurudutta has been a scientific administrator with impactful leadership experience, having served as Director (Addl.), Senior Research Scientist 'G' (Indian Defence R&D Service, MoD, Govt. of India), and the founding HoD of the Department of Stem Cell, Tissue Engineering and Gene Therapy for over 20 years. He has also served as a key member on various task forces and committees of ICMR, DBT, and DST. Furthermore, as a scientific member of the prestigious international Programmes Advisory Committee (PAC) of the DST for over 15 years, he was responsible for fostering bilateral cooperation in research programmes with several countries.

Prof. Gurudutta obtained his PhD from the University of Delhi. As a NASA/NABRI post-doctoral fellow in the Mission to Mars project at the prestigious University of Pennsylvania (UPENN), USA, and Brookhaven National Laboratory (NY), USA, he contributed significantly to understanding the effects of high-LET space particle radiation (Ti, Fe, Pr, Si) on human stem cells, as well as to the development of protectors. Additionally, as a FAPESP post-doctoral fellow at the University of São Paulo, he made significant contributions to understanding the role of the middle-T antigen of the polyoma virus in the proliferation of glioblastoma cells. He was also awarded the NRC (Canada) post-doctoral fellowship.

Further, during his long tenure at the Defence Research & Development Organisation (DRDO), Delhi, he made several pioneering and original contributions to molecular stem cell biology, regenerative medicine, gene therapy, tissue engineering, molecular signalling, and particularly to clinically relevant human stem cell response and fate research. In this line, he spearheaded major R&D projects with DRDO mandate and achieved several milestones, including the development of novel human stem cell targeting, shielding nano-formulations, NMR 7-9 Tesla (Medical) SC-tracking methods, several fate-modifying molecules, and composite-biomaterial-based devices to enhance the application potential of stem cells in therapeutics. He has published more than 100 research articles in high-impact international and national journals, over 100 conference presentations, and holds over 12 granted or registered patents with i10-index of 44/h-index 25. More than 20 PhD scholars and numerous masters and graduate students have benefited immensely from his dedicated supervision and guidance.

The originality and translational impact of his work are highlighted by several remarkable milestones:

  • (a) The discovery of the unique potential of Pluronic F-127 to sequester pla

PREVIOUS POSITIONS/ EXPERIENCE

WORK EXPERIENCE

Highlights

  • Leading advanced teaching and research initiatives in biotechnology, regenerative biology, gene therapy, stem cell engineering, & molecular sciences.
  • Driving high-impact regenerative and translational research programs, integrating cutting-edge laboratory tools and bioengineering platforms.
  • Supervising Ph.D, M.Tech and postgraduate scholars, strengthening scientific mentoring, research integrity, and publication quality.
  • Developing interdisciplinary academic–research collaborations with national institutes, defence labs, and global universities.
  • Enhancing curriculum frameworks & academic governance, ensuring alignment with emerging biomedical technologies & global scientific standards.
  • Strengthening institutional research capability by enabling innovation-driven projects, faculty development, and industry partnerships.

Scientific & Academic positions

  • Distinguished Fellow (June-2026 - till today), Dept. of Biotechnology, Delhi Technological University (DTU), Delhi.
  • Hon. Professor (Nov 2024 - till today), Maharaja Surajmal Brij University (Govt. of Rajasthan), Bharathpur, Rajasthan.
  • Guest Professor (Feb 2025 - Apr 2025), Dept. of Biological Sciences & Engineering, Netaji Subhas University of Technology, New Delhi.
  • Professor (Emeritus Full Time) (Feb 2023-Feb 2025), Dept. of Biological Sciences & Engineering, Netaji Subhas University of Technology, New Delhi
  • Scientist “G” & Director (Addl.) (July 2016-Aug 2020), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • HoD (Founding Head) (2006-2020), Dept. of Stem Cell, Tissue-Engineering & Gene Therapy Research, Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “G” (DRDS Cadre) (July 2016-Aug 2020), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “F” (July 2011-June 2016), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “E” (July 2006-June 2011), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “D” (July1999-June 2005), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “C” (July 1992-June 1998), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • Scientist “B” (Mar 1988-June 1992), Institute of Nuclear Medicine & Allied Sciences (INMAS), Dept. of Defence Research & Development (DRDO), Govt. of India, Delhi.
  • ICMR Research Project Fellow (Sept. 1986-Nov 1987), Dept. of Biochemistry, Indian Institute of Science (IISc), Bangalore.
  • Junior Research Fellow (1st CSIR–NET) (July 1984-Aug 1986), Department of Biochemistry, Karnataka University.
  • UGC Junior Research Fellow (May 1983-July 1984) School of Life Sciences, Central University of Hyderabad.

Experience

  • Research & Teaching >37 yrs
  • Administrative/Management Experience >30 yrs?
  • Secretary-OGPF (Officers General Purpose Fund)(1993-1995): INMAS
  • Officers-in-Charge/Secretary (1993-1995)( 2006-2012): Jour. Club Seminar, INMAS
  • Representative (1996-1997): Delhi Defense Science Forum (DSF)
  • Member (1998-2020): DRDO/Institutional level committees on Security, Selection, Conferences, Purchases, Procurement/Stores meetings, Extramural Reports / Projects evaluation and other issues, negotiation of material / technology transfer for project work, collaboration & Consultations (Intl + Natl) for our project, Grant writing, Assisting Scientific Director, INMAS-Council
  • Officer-in-charge (1994-1997): Officers Grievances committee          
  • Member (2009-2021): International Program Advisory committee (PAC), Life Sciences/Bio-Medical Sciences/Medical Biology for International Co-operation, Dept. of Sciences & Technology, Min. of S & T, GOI      
  • Member (2011-2012): Defence Technology Vision – 2050. Sub-committee on Life Sciences, DRDO HQ, Min of Defence 
  • Member (2010-2020): Scientific Advisory Committee Post-Graduate Institute of Medical Sciences, Pt.Bhagwat Dayal Sharma, University of Health Sciences, Rohatak, Haryana
  • Member (2012-2020): Institutional Committee on Stem Cell Research & Therapy, (IC-SCRT), Reporting to National-Apex Committee on Stem Cell Research in India, Bangalore to carry our all-regulatory functions related to Ethical & Safety issues of SCR
  • Chairman (2013-2020): Life Sciences Research Board (LSRB) (INMAS Chapter), DRDO – LSRB Project evaluation committee
  • Chairman (2013-2020): INMAS Resource Council
  • Chairman (2013-2020): INMAS Technology Council
  • Executive Member. Biotechnology Society of India (Current).

     

     

TEACHING (COURSES TAUGHT)

SUBJECT TAUGHT (CLASS)

  • Radiation Biology (MSc, MD, PhDs)
  • Stem Cell Biology (MSc, MD, PhDs)
  • Genetic-Engineering (MSc, PhDs)
  • Research Methodology ((MSc, MD, PhDs)
  • Concepts in modern biology (MTech)
  • Introduction to Biotechnology (BTech)
  • Transgenics part of Plant Genomics & Transgenics (BTech)
  • Public Health Management (BTech)
  • Current Topics in Energy and Environment (BTech)
  • Concepts in modern biology Lab (BTech)
  • Molecular & Cellular Diagnostics (BTech)
  • Structural Biology (theory)(B.Tech)
  • Cell Biology (BTech)
  • In addition to R&D, teaching, supervised PhD, M.D, MSc, BTech, and MTech Research projects

MEMBERSHIPS

ELECTED TO FELLOWSHIPS

  • Fellow, Royal Society of Chemistry FRSC (530962) London, UK
  • Fellow, Royal Society of Medicine FRSM (00706483) London, UK
  • Fellow, Indian Society of Chemistry FICS (F7649)
  • Fellow, Irish Institute of Chemistry FIIC (F0473) Dublin
  • Fellow, Royal Academy of Medicine of Ireland FRAM (2014) Dublin
  • Fellow, Royal Society of Biology FRSB (P0121350) UK
  • Fellow, National Academy of Biological Sciences FNA Biol Sci’s (108-2015)  India

MEMBERSHIPS

  • Member, American Society of Biochemistry and Molecular Biology, USA (M-20240)
  • Member, Royal Australian Institute of Chemistry, Charted Chemist MARC CChem (46244) Australia
  • Member-Executive, Biotechnology Society of India
  • Member, Stem Cell Research Forum of India, India
  • Member, Society for Tissue Engineering & Regenerative Medicine (India)
  • Member, Indian Society of Radiation Biology
  • Member, Australian Society of Stem Cell Research
  • Member, Indian Association of Bio-Medical Scientists
  • Member, Indian National Science Congress
  • Member, (Life) National Academy of Biological Sciences (LM022-15), India

PUBLICATIONS

*Corresponding author

  1. *β2 Integrin Antagonism, A Potential Mechanism to Sensitize CML Cells to Therapy as Revealed from Genetic Response to Radiation and LiCl. Yogesh Kumar Verma, Namrata Yadav, Subodh Kumar, Gangenahalli Ugraiah Gurudutta. Research Square. September 29th 2021. DOI: https://doi.org/10.21203/rs.3.rs-885452/v1
  2. Multifunctional, adhesive PDA-coated bioactive glass reinforced composite hydrogel for regenerative wound healing. Sarika Tomar, Rakesh Pandey, Priyanka Surya, Ranjan Verma, Rashi Mathur, Gurudutta Gangenahalli, Sweta Singh*. ACS Biomaterials and Engineering (ACS Pub, USA) 9. 3. 1520-1540. 2023.IF= 4.478
  3. *VCAM1 Mediated Targeting of Human Hematopoietic Stem Cells to Bone Marrow is Effective in Conferring Regeneration and Survival in Lethally Irradiated Mice. Swati Gupta & Gurudutta Gangenahalli*. Transplantation and Cellular Therapy USA (Elsevier). 28. 10. 667. 2022. IF: 5.7
  4. *Pluronic-F127/Platelet Micro-vesicles nanocomplex delivers stem cells in high doses to the bone marrow and confers post-irradiation survival. Vikas Chander, and Gurudutta Gangenahalli*. Nature Scientific Reports. 10. 156. 2020. http://doi.org/10.10301s41598-019-57057-8, 2020. IF=4.379
  5. *PU.1 mimic synthetic peptide selectively binds with GATA-1 and allow c-Jun PU.1 binding to enhance myelopoiesis by stem cells. Pawan Kumar Raghav and Gurudutta Gangenahalli*. International Journal of Nano-Medicine USA (Dove Press). 16: 3833–3859. 2021. IF = 5.11
  6. *Therapeutic Prospective of Infused Allogenic Cultured MSCs in Traumatic Brain Injury Mice: A longitudinal 1H MRS assessment. Sushant Mishra, Subash Kushu and Gurudutta Gangenahalli*. Stem Cells (Translational Medicine) (Alpha Med, USA). 5. 1-14. 2016. IF=6.9
  7. *LiCl containing thermosensitive formulation improves homeostasis, wound healing and hair regrowth. Yogesh Kumar Verma, Ranjan Verma, Ajay Kumar Singh & Gurudutta Gangenahalli*. Regenerative Engineering & Translational Medicine USA (Springer Nature). 7. 362-378. 2021. Doi 10.1007/s40883-020-00148-0, 2020. New journal, IF=2.4
  8. *Survival genes expression analysis following ionizing radiation in LiCl treated cells. Yogesh Kumar Verma, Ajay Kumar Singh & Gurudutta Gangenahalli*. International Journal of Radiation Biology (Taylor & Francis USA). 5. 96.  671-688. 2018.  IF=1.68
  9. In vitro evaluation of magnesium aluminate (MgAl204) spinel ceramic based polyphasic composite scaffold for craniofacial bone tissue-engineering. Anu Sharma, Manu Krishnan*, Gurudutta Gangenahalli, Seema Saraswathy, Paiya Biswas, Roy Johnson, Kurian Mathew Abraham, Satish R Iyer. Ceramic International (Elsevier). https://doi.org/10.1016/J.ceramint.2021.01.229. IF=3.8
  10. *Fibronectin modified alginate coating enhances cell targeting and homing to bone marrow in BALB/c mice. Yogesh Kumar Verma. Gangenahalli Ugraiah Gurudutta*. Journal of Microencapsulation (Taylor & Francis, USA). 5 Jan 2022. https://doi.org/10.1080/02652048.2022.2025934. IF=3.142
  11. *Neuroprotective response and efficacy of intravenous administration of mesenchymal stem cells in traumatic brain injury mice. Sushanta Kumar Mishra, Subash Khushu, and Gurudutta Gangenahalli*. European Jour. of Neuroscience (Elsevier). 54: 4392-4407, 2021. https://doi.org/10.1111/ejn.15261. IF=3.38
  12. *Peroxisome proliferator activated receptor gamma sensitizes non-small lung carcinoma to gamma irradiation induced apoptosis. Simran Kaur, Alo Nag, Gurudutta Gangenahalli and Kulbhushan Sharma*. Frontiers in Genetics (Stem Cell Research). 13. 2019. https://doi.org/10.3389/fgene.2019.00554. IF=4.1
  13. *A Distinctive MRI-Based Absolute Bias Correction Protocol for the Potential Labelling and In Vivo Tracking of Stem Cells in a TBI Mice Model. Sushant Mishra, Subhas Kushu & Gurudutta Gangenahalli*. Methods in Molecular Biology (Springer). DOI 10.1007/7651_2019_277 2 © Springer Science + Business Media New York 2019. IF=10.7
  14. *Data mining and structural analysis for multi-tissue regeneration potential of BMP-4 and activator drugs. Nishant Tyagi, Kirtida Gambhir, Deepak Sharma, Gurudutta Gangenahalli, and Yogesh Kumar Verma*. Journal of Bio-Molecular Structure and Dynamics. https://doi.org/10.1080/07391102.2022.2067899. IF=3.93
  15. *Microarray illustrates enhanced mechanistic action towards osteogenesis for magnesium aluminate spinel ceramic-based polyphasic composite scaffold with mesenchymal stem cells and bone morphogenetic protein 2. Anu Sharma, Manu Krishnan, Gurudatta Gangenahalli*, Seema Saraswathy, Roy Johnson, Satish R. Iyer. Journal of Biomedical Materials Research Part B: Applied Biomaterials. https://doi.org/10.1002/jbm.b.35051. March. 2022. IF=3.4
  16. Minimizing the negative charge of Alginate facilitates the delivery of negatively charged molecules inside cells. Nishant Tyagi, Kirtida Gambhir, Rakesh Pandey, Gurudutta Gangenahalli, Yogesh Kumar Verma*. Journal of Polymer Research (Springer). 1. 2022.  https://doi.org/10.1007/s10965-021-02813-6. IF=3.097
  17. Therapeutics effect of mesenchymal stromal cells in reactive oxygen species-induced damages. Subodh Kumar, Ranjan Verma, Nishant Tyagi, Gurudutta Gangenahalli, Yogesh Kumar Verma*. Hum Cell (Springer). 35. 1. 37-50. 2022.  doi: 10.1007/s13577-021-00646-5. IF= 4.174
  18. A brief molecular insight of COVID?19: epidemiology, clinical manifestation, molecular mechanism, Cellular tropism and immuno?pathogenesis.  Sweta Singh, Rakesh Pandey, Sarika Tomar, Raunak Varshney, Darshika Sharma, Gurudutta Gangenahalli*. Molecular and Cellular Biochemistry (Springer). 30. 1- 16. 2021. IF=3.396
  19. Interplay of reactive oxygen species (ROS) and tissue engineering: a review on clinical aspects of ROS-responsive biomaterials. Nishant Tyagi, Kirtida Gambhir, Subodh Kumar, Gurudutta Gangenahalli, Yogesh Kumar Verma*. Journal of Materials Science (Springer).  30. 2021. IF=4.22
  20. *COVID-19 and its therapeutics: Special emphasis on Mesenchymal Stem Cells based Therapy. Yogesh Kumar Verma, Ranjan Verma, Nishant Tyagi, Amanpreet Behl, Subodh Kumar, Gurudutta U Gangenahalli*. Stem Cell Reviews & Reports (Springer Science). 2020. 10.1007/s12015-020-10037-2. IF=5.316
  21. *Myelopoiesis specific gene expression profiling in human CD34 hematopoietic stem cells. Madhuri Joshi & Gurudutta Gangenahalli*. Gene-Expression patterns (Elsevier). 37. 119-128. 2020. IF=2.17
  22. *Emerging strategies to enhance the delivery of hematopoietic stem cells to the bone marrow for conferring post- irradiation survival. Vikas Chander and Gurudutta Gangenahalli*. Exp Cell Res. 2020 May 1. 390. 1. 111954. IF=3.9
  23. *Analysis of molecular switch between leukocyte and substrate adhesion in bone marrow endothelial cells. Gupta S & Gangenahalli G*. Life-Sciences (Elsevier) 238. 116981. 2019. DOI: 10.1016/j.lfs.2019.116981PMID: 31639394. IF=5.0
  24. *Hematopoietic stem cell crucial molecular targets and factors regulating hematopoiesis. Pawan Kumar Raghav, Gurudutta Gangenahalli*. Journal of Stem Cell Research & Therapy. 8.11. 2-16. 2018.  DOI.10.4172/2157- 7633.1000441. IF= 2.76
  25. *Stem Cell Factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblast cells. Pawan Kumar Raghav, Ajay Kumar Singh, Gurudutta Gangenahalli*. PLoS1 (USA). 13. 11. e0206364. https://doi.org/10.1371/journal. pone.0206364 2018. IF= 2.766
  26. *Stem cell factor and NSC87877 synergism enhances c-Kit mediated proliferation of human erythroid cells. Pawan Kumar Raghav, Ajay Kumar Singh, Gurudutta Gangenahalli*. Life-Sciences (Elsevier). 84-97. 214. 2018. 10.1016/j.lfs.2018.09.055. 2018. IF= 5.03
  27. *Homing and Tracking of Iron Oxide Labelled Mesenchymal Stem Cells After Infusion in Traumatic Brain Injury Mice: a Longitudinal In Vivo MRI Study. Mishra SK, Khushu S, Singh AK, Gangenahalli G*. Stem Cell Rev & Reports (Springer). 2018 Jun 17. doi: 10.1007/s12015-018-9828-7. IF=5.316
  28. *Cell encapsulation potential of chitosan-alginate electrostatic complex in preventing natural killer and CD8+ cell- mediated cytotoxicity: an in vitro experimental study. Vikas Chander,Ajay Kumar Singh & Gurudutta Gangenahalli*. Jour. of Microencapsulation. Micro and Nanocarriers (Taylor & Francis. USA). 522-532. 35. 6. 2018.  https://doi.org/10.1080/ 02652048.2018.1516827. IF=2.04
  29. *A change in structural integrity of c-Kit mutant D816V causes constitutive signaling. Pawan Kumar Raghav, Ajay Kumar Singh and Gurudutta Gangenahalli*. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis (Elsevier). 28-38. 808.  2018. IF=2.46
  30. *Analysis of signal network in hematopoietic stem cells determining the stem cell fate. Swati Sharma, Gurudutta U Gangenahalli* and Upma Singh. European Journal of Pharmaceutical and Medical Research (Society of Advance Health-care Research). 5. 5. 391-398. 2018. IF=4.897
  31. *Stem Cell Genes Synergism: Elucidation of the Mechanistic Basis of Response Induced by Cytokine Combination (IL-3, FLT-3, and SCF). Swati Sharma, Gurudutta U Gangenahalli*, and Upma Singh. Journal of Stem Cells (Nova Science Publishers). 12. 4. 2018.
  32. *Early monitoring and quantitative evaluation of macrophage infiltration after experimental traumatic brain injury: a magnetic resonance imaging and flow cytometric analysis. Sushanta Kumar Mishra, B. S. Hemanth Kumar, Subash Khushu, Ajai K Singh and Gurudutta Gangenahalli*. Molecular and Cellular Neuroscience (Elsevier). 25-34. 78. 2017. IF=3.3
  33. *A Hypothetical Tool for Integrated Omics, Drugs and Clinical Stem Cell Data Analysis. Yogesh Kumar Verma, Gurudutta Gangenahalli*. Defence Life Science Journal, 2, 3. 354-357. 2017 (DESIDOC Press, India).
  34. *Data mining for drug repurposing and new targets identification for radioprotection. Yogesh Kumar Verma, Gurudutta Gangenahalli*. Defence Life Science Journal 2 (3). 343-353. 2017 (DESIDOC Press, India).
  35. *Potential stem cell labeling ability of poly-L-lysine complexed to ultra-small iron oxide contrast agent: An optimization and relaxometry study. Sushant Mishra, Subash Khushu and Gurudutta Gangenahalli* Experimental Cell Research (Elsevier). 339. 2. 10. 427–436. 2015. IF=3.378
  36. *Gene expression profiling of human c-Kit mutant D816V. Shilpa Sharma, GURUDUTTA Gangenahalli*. Journal of Cancer Therapy (Scientific Research Publishing). 7. 439-454. 2017. IF=0.65
  37. *Biological effects of iron oxide-protamine sulfate complex on mesenchymal stem cells and its relaxometry based labeling optimization for cellular MRI. Sushanta Kumar Mishra, Subash Khushu, Gurudutta Gangenahalli*. Experimental Cell Research. 351. 59-67. 2017. IF=3.905
  38. *Umbilical Cord Blood Transplantation: Clinical Challenges. Shilpa Sharma and Gurudutta Gangenahalli* International Journal of Stem Cell Research and Transplantation (Sci Doc Publishers, England). 3. 6. 134- 141. 2015. IF=1.316
  39. *Mesenchymal stem cells from orthodontic premolar teeth. Manu Krishnan, Anu Sharma, Seema Saraswathi, Gurudutta Gangenahalli, Sanjay Londhe, Ajay Kumar Singh, Velu Nair. Medical Journal of Armed Forces, India. 1-8. 2018. https://doi.org/10.1016/j.mjafi.2018.08.006 0377-1237. IF= 0.47
  40. Maxillofacial Musculoskeletal Diseases. Manu Krishnan*, Gurudutta Gangenahalli, Satish R. Iyer and Sanjay Londhe. Austin Journal of Musculoskeletal Disorders (Austin Publishing Group). 2. 2. 1-20. 2015.
  41. *Adult hematopoietic stem cells: Niche cross-talks to affect the cell. Shilpa Sharma and Gurudutta Gangenahalli* Niche Journal (Journal of Cellular Therapy & Regenerative Medicine Society. Turkey). DOI:10.5152/Niche.2015.214.
  42. *Epigenetic regulation of hematopoietic stem cells. Shilpa Sharma and Gurudutta Gangenahalli*. International Journal of Stem Cells (Sci Forchen, Korea) 9. 36-43. 2016. IF=2.78
  43. *Electrophoretic detection of alginate by Hematoxylin and Eosin fluorescence: Implications in cell encapsulation/ tissue engineering. Yogesh Verma and Gurudutta Gangenahalli*. Reactive & Functional polymers (Elsevier). 102. 130–136. 2016. IF=3.151
  44. *Increased transverse relaxivity in ultra-small superparamagnetic iron oxide nanoparticles: Applications as MRI contrast agent for biomedical imaging. Sushant Mishra, Subash Kushu and Gurudutta Gangenahalli*. Contrast Media and Molecular Imaging (John Wiley & Sons). 11(5). 350-361. 2016. IF= 3.0
  45. *Conformal coating (encapsulation) of human single cells by biodegradable chitosan nano-particles and their response assessment in vitro and in vivo. Siddharth Pandey, and Gurudutta Gangenahalli * et al. Journal of Pharmaceutics and Drug Delivery (American Scientific Publishers). 2. 227-234. 2014. IF= 1.0
  46. *Transgene expression study of CXCR4 active mutants: Potential prospects in up-modulation of homing and engraftment efficiency of hematopoietic stem/progenitor cells. Menka Sharma, Farhat Afrin, Rajendra P Tripathi, Gurudutta Gangenahalli*. Cell Adhesion & Migration (Taylor & Francis, USA).  8. 4. 384-388. 2014. IF=3.566
  47. *Human T-Cell line (Jurkat cell) Encapsulation by Nano-organized Polyelectrolytes and their Response Assessment in vitro and in vivo." Siddharth Pandey, GURUDUTTA Gangenahalli*, Farhat Afrin et al. Journal of Nanoparticle Research. (Springer). 15. 1793. 2013. IF= 2.179
  48. *High-throughput transcriptome profiling of bone marrow derived human Mesenchymal stem cells reveal GS3βKinase inhibition as their priming target to stimulate the differentiation towards osteoblastic lineage Neeraj Kumar Satija, Farhat Afrin, R P Tripathi, GURUDUTTA Gangenahalli*. PLoS1 (USA). 8.1. 1-12. 2013. IF= 4.8
  49. *Regulated expression of CXCR4 constitutive active mutants’ revealed up-modulated chemotaxis and positive loop of genes crucial for CXCR4 mediated homing and engraftment of hematopoietic stem cells. Menka Sharma, Farhat Afrin, R P Tripathi, GURUDUTTA Gangenahalli*. Journal of Stem Cell & Regenerative Medicine (German Society for Stem Cell Research (GSZ). 9. 1. 19. 2013. IF=4.5
  50. *Enhanced hetero-dimerization of Bax by Bcl-2 mutants improves irradiated hematopoietic cell survival. Yogesh Kumar Verma, Pawan Kumar, Raghav, H G Raj, GURUDUTTA U Gangenahalli*, et al. Apoptosis (Springer) USA). 18.1.212-225. 2013. IF=4:788
  51. *Molecular Dynamics Simulations of Bcl-2 Protein to Predict the Structure of its Unordered Flexible Loop Domain. Pawan Kumar Raghav, Yogesh Kumar Verma, GURUDUTTA Gangenahalli* et al. Journal of Molecular Modelling (Springer, USA) 18. 5. 1885-1906. 2012. IF= 1.9
  52. *Screening of pro-apoptotic peptides for Bcl-2 knockdown: Implications in Cancer Diagnosis and Treatment. Pawan Kumar Raghav GURUDUTTA Gangenahalli* et al. International Journal of Biological Macromolecules (Springer, USA). 50(3). 796-814. 2012. IF=2.5
  53. *Three-dimensional structure Prediction and Interaction of CD34 with Crk-L SH3 Domain. G.U. GURUDUTTA*, Vimal kishor Singh, Yogesh Verma, Pallavi Gupta, Ramesh Chandra, Shweta Gulati, and Pratibha Mehta Luthra, Stem Cells and Development (Mary Ann Liebert Inc. USA) 14. 469. 2005. IF=4.459
  54. *Structural conservation of residues in BH1 and BH2 domains of Bcl-2 family proteins. Gangenahalli U. GURUDUTTA*, Yogesh Kr Verma, Vimal Kishor Singh, Pallavi Gupta, H.G. Raj, R.K. Sharma, Ramesh Chandra. FEBS Letters (Wiley online library) 579. 17. 3503-3507. 2005. IF=3.4
  55. *Evaluation of potential tracer ability of 99mTc-labelled acetylated LDL for scintigraphy of LDL scavenger receptor sites of macrophageal origin. G.U. GURUDUTTA*, A.K.Babbar, Soumya Pati, R.K.Sharma. Nuclear Medicine and Biology (Elsevier, USA). 28. 3. 235. 2001. IF= 3.01
  56. *Monitoring of the in-situ thymine photo-adduct using UV irradiated DNA antibody F(ab)2 fragment. G.U GURUDUTTA, Chauhan, Viney Jain*, Ramesh Chandra. Bio Chem. Soc. Transactions/Communications (London).19.1991. S-4925. IF=3.71
  57. *Characterization of glutamine synthetase and ATPases in a mutant strain of the cyanobacterium Nostoc-muscorum capable of metabolizing methylamine as a source of nitrogen. G.U. GURUDUTTA, Rita Ghosh, KMR Nambiar and H.N.Singh*. J. Plant. Physiol (Elsevier GmbH). 127. 323-329. 1987. IF=3.45
  58. *The structural insights of stem cell factor receptor (c-kit) interaction with tyrosine phosphatase-2 (ShP-2): An in-silico analysis. Soumya Pati. G U GURUDUTTA* et al. Bio-Med Central Research Notes. (BMC) (USA) (Open Access). 3:14-43. 2010. IF=1.66
  59. *Antigenic manifestation of the free and intact UV (250nm) irradiated deoxyribonucleic acid. Ramesh Chandra, G.U. GURUDUTTA*, UPS Chauhan. Clin. Chem. Enzy. Comm. (Harwood Academic Publishers, Amsterdam/Netherlands). 7. 317-330. 1997.
  60. *Hematopoietic stem cell antigen CD34: role in adhesion or homing. G.U. GURUDUTTA *, Vimal Kishor Singh, Yogesh Verma, Pallavi Gupta, Ramesh Chandra, Shweta Gulati, and Pratibha Mehta Luthra, Stem Cells and Development (Mary Ann Liebert Inc. USA). 15. 305-313. 2006. IF=4.459
  61. *Cell death regulation by B-cell lymphoma protein. Yogesh Kr Verma, Gangenahalli U. GURUDUTTA *, Vimal Kishor Singh, Pallavi Gupta, H.G. Raj, R.K. Sharma, Ramesh Chandra. Apoptosis (Springer, USA) 11. 5. 459- 471. 2006. IF=4.788
  62. *Stem cell fate specification: Role of master regulatory switch, transcription factor PU.1 in differential hematopoiesis. Gangenahalli U. GURUDUTTA*, Pallavi Gupta, Daman Saluja, Yogesh Kr Verma, Vimal Kishor Singh, R.K. Sharma, Ramesh Chandra, T Ravindranath. Stem Cells and Development (Mary Ann Liebert Inc. USA) 14. 2. 140-152. 2005. IF=4.459
  63. *PU.1: An ETS family transcription factor that regulates leukemeogenesis besides normal hematopoiesis. Gangenahalli U. GURUDUTTA*, Pallavi Gupta, Daman Saluja, Yogesh Kr Verma, Vimal Kishor Singh, R.K. Sharma, Ramesh Chandra, T Ravindranath. Stem Cells and Development (Mary Ann Liebert Inc., USA) 15. 4. 609-617. 2000. IF=4.459
  64. *Mesenchymal stem cells: molecular targets for tissue engineering. Neeraj Kumar Satija, G.U. GURUDUTTA*, Shilpa Sharma, Farhat Afrin, Pallavi Gupta, Yogesh Kumar Verma, Vimal Kishor Singh, R.P.Tripathi. Stem Cells and Development (Mary Ann Liebert Inc. USA) 16. 1-17. 2007. IF=4.459
  65. *Stem cell c-kit and Hoxb4 genes: critical roles and mechanisms in self-renewal, proliferation and differentiation. Shilpa Sharma, Gangenahalli U. GURUDUTTA *, Neeraj Kumar Satija, Soumya Pati, Farhat Afrin, Pallavi Gupta, Yogesh Kumar Verma, Vimal Kishor Singh, R.P.Tripathi. Stem Cells and Development (Mary Ann Liebert Inc. USA). 15. 755-778. 2006. IF=4.459
  66. *Mesenchymal stem cell-based Therapy: A New Paradigm in Regenerative Medicine. Neeraj Kumar Satija, Vimal Kishor Singh, Yogesh Kumar Verma, Pallavi Gupta, Shilpa Sharma, Farhat Afrin, Menka Sharma, Pratibha Sharma, R. P. Tripathi and G U GURUDUTTA*. Journal of Cellular and Molecular Medicine (Wiley Blackwell, USA). 13. 11-12. 4385-4402.2010. IF=5.9
  67. *PU.1 and partners: regulation of hematopoietic stem cell fate in normal and malignant hematopoiesis. Pallavi Gupta, Gangenahalli U GURUDUTTA*, Daman Saluja, R P Tripathi et al. Journal of Cellular and Molecular Medicine (Wiley Blackwell, USA). 13 .4349-4363. 2010. IF=5.9
  68. *SDF-1/CXCR4 signaling in homing and engraftment of bone marrow hematopoietic stem cells. Menka Sharma, Farhat Afrin, Neeraj Satija, R P Tripathi, G.U. GURUDUTTA* et al. Stem Cell & Development (Mary Ann Liebert, USA). 1-12. 6. 20. 2011. IF= 4.45
  69. *Induced Pluripotential Stem Cells: Fundamentals and Applications of the Reprogramming Process and its Ramifications on Regenerative Medicine. Bhavita Walia, Neeraj satija, R P Tripathi, GURUDUTTA Gangenahalli*. Stem Cell Reviews & Reports (Springer. USA). 8. 100-115. 2012. IF=5.7
  70. *Stem cell therapy: A novel and futuristic treatment modality for disaster injuries. Neeraj Kumar Satija, R P Tripathi, G.U. GURUDUTTA *, et al. Indian Journal of Medical Research (ICMR), 135 (Jan). 15-25. 2012. IF=2.375
  71. *Important role of science and technology in making modern industrial society. Pawan Kumar Raghav, Siddharth Pandey, Neeraj Satija, Yogesh Kumar Verma, Gurudutta U Gangenahalli. Science and Culture (DRDO and DESIDOC, ISBN: 978-81-86514-40-5). 29-34. 2013.
  72. *Biochemical Modulation: Potential role of anti-metabolites in cancer therapy. G.U GURUDUTTA*. Ramesh Chandra, UPS Chauhan*. Jour. Basic & Appl. Bio-Medicine (Acad of Bio-Medical Scientists. India). 4. 3. 7- 22.1996.
  73. *Cancer therapeutic non-nucleotide anti-metabolites. G.U.GURUDUTTA*, Ramesh Chandra. J. Basic & Appl. Bio-Medicine (Acad. of Bio-Medical Scientists, India). 6. 3. 1-16. 1998.
  74. *In Vivo specific hybridization ability of radio-labeled anti-sense oligo-nucleotides with tumor associated oncogene mRNA: Potential utility for targeted scintigraphy in Nuclear medicine. G.U. GURUDUTTA *. UPS Chauhan. J. Basic & Appl. Bio-Medicine (Acad. of Bio-Medical Scientists. India). 5. 1. 1-17. 1997.
  75. *Countering low-linear transfer (LET) & high-LET radiation exposure with pro-methyl Hoechst (PMH) & EUK- 134 (Mg-Salen complex): Radio-protection of normal human CD34+ stem cells in a simulated deep space environment. G U GURUDUTTA, John Millholand, Ana Kolata, Paula Bennett, Betsy Sutherland and Alan Gewirtz*. Blood (USA) 104. 11. 4158. 2004. IF=9.8 (in 2004)
  76. *The CD34 antigen molecular domains implied in potential homing and engraftment of hematopoietic progenitors. G.U. GURUDUTTA*, Vimal Kishor Singh, Soumya Pati, Yogesh Verma, Pallavi Gupta, Rajat Kumar, Rakesh Kumar Sharma, Ramesh Chandra, and Pratibha Mehta Luthra, Molecular Therapy (USA) 9. S246. 2004. IF=6.81(in 2004)
  77. *Homology modeling of anti-apoptotic protein Bcl-2. Yogesh Kr Verma, Gangenahalli U. GURUDUTTA*, Vimal Kishor Singh, Pallavi Gupta, H.G. Raj, R.K. Sharma, Ramesh Chandra. Bio-informatics Trends 3. 3. 23-27. 2005.
  78. *Homology modeling of human stem cell antigen CD34. Vimal K Singh, Gurudutta U Gangenahalli et al. Bio- informatics Trends (India). 3. 1. 33-45. 2008.
  79. *Modifications of the energy metabolism by anti-metabolites: evaluation of excision of DNA thymine dimmers in activated human lymphocytes by immunochemical technique. G.U. GURUDUTTA*, UPS Chauhan, Ramesh Chandra. J. Basic & Appl. Bio-Medicine (Academy of Bio-Medical Scientists. India). 4 (2). 1996. 27-34.
  80. *Hematopoietic Stem Cell Transcription Factor PU.1 with Mutated beta3/beta4 Domain Selectively Elicits Myeloid Differentiation. Pallavi Gupta, GURUDUTTA Gangenahalli*, Daman Saluja*, Jyoti Zack et al. Nature (Proceedings) (NPG) 29 December 2010, 17:19 UTC. (Prepublication of research & preliminary findings) http://precedings. nature.com /documents/ 5453/ version/1).
  81. *Stem cell antigen CD34 in native and engineered form alters its binding ability to stromal cells and ligands: A classic example of clinical benefits of therapeutic genetic engineering of stem cells in transplantation. GURUDUTTA Gangenahalli*, Vimal Kishor Singh*, et al. Nature (Proceedings) (NPG) 29 December 2010 17:19 UTC (Prepublication of research & preliminary findings). (http://precedings.nature. com/documents/5454/version/1).
  82. *High-Throughput Transcriptome Profiling of Human Mesenchymal Stem Cells Reveals a Role for Wnt/GSK-3 Signaling in Their Hypo-immunomodulation. GURUDUTTA Gangenahalli*, Neeraj Kumar Satija, Farhat Afrin, R P Tripathi. Nature (Preceding’s) (NPG) 07 January 2011 13:56 UTC (Pre-publication research and preliminary findings). http://precedings.nature.com/documents/ 5512/version/1.
  83. *Open-Source Bio-perl Programs for Biological Sequences. Pawan Kumar Raghav, Arvind Singh, Kumud Sarin, Yogesh Kumar Verma, GURUDUTTA Gangenahalli* et al. Bio-informatics Trends (India). 5. 3&4. 60-64. 2010.
  84. *Hypothetical model for the suppression of stress induced apoptosis in hematopoietic stem cells. Gangenahalli U. GURUDUTTA *, Yogesh Kr Verma, Vimal Kishor Singh, Pallavi Gupta, H.G. Raj, R.K. Sharma, Ramesh Chandra. Indian Journal of Nuclear Medicine (ISNM) 21 (1). 1-17. 2006.
  85. *Genetically-engineered BCL-2 functional variants over-expression induces radio-resistance in Hematopoietic cells. GURUDUTTA U Gangenahalli*, Yogesh Kumar verma, Pawan Kumar Vermas Raghav, H G Raj et al. Journal Advanced Biotechnology (Samanthi Publications, Chennai). 10. 5. Nov 2010.
  86. *Regulation of hematopoietic activity involving new interacting gene partners RAGC & PSMC2, CKAP4 & MANF and CTR9 & CNTNAP2). Swathi Sharma, Gurudutta U Gangenahalli*, Upma Singh. Cell Bio. 9. 3. Sept. 30. 2020. DOI: 10.4236/cellbio.2020.93007. IF=0.5.
  87. *Effect of iron oxide contrast agent in combination with various transfection agents during mesenchymal stem cells labelling: An in vitro toxicological evaluation. Sushant Mishra, Subash Khushu* and Gurudutta Gangenahalli*. Toxicology In vitro (Elsevier). 50. 179-189. 2018. IF=3.4  
  88. Publications under Revision:
  89. *Cross-antagonism relinquished genetically-engineered PU.1: A potential tool in nanoform to elicit emergency myelopoiesis & specific gene-expression conferring the infection resistance after radiation exposure. Madhuri Joshi, Pallavi Gupta and Gurudutta Gangenahalli*. Experimental Hematology. 2022. IF=3.08
  90. *Synergistic effect of cell surface receptor masking, novel Bax antagonist peptide and LiCl improves homing and engraftment in bone marrow of BALB/c mice. Yogesh Verma and Gurudutta Gangenahalli*. Stem Cell Reports (Springer). 2019. IF=7.0
  91. *Structural and functional evaluation of novel Bax antagonist peptide for enhanced cell survival.  Yogesh Kumar Verma, Kirtida Gambhir, Nishant Tyagi, Prateek Paul, and Gurudutta Gangenahalli.  Molecular Therapy (Cell Press, USA) 2022. IF=11.45
  92. *LiCl, Bax, antagonist peptide and ascorbic acid combination rescues lethally irradiated BALB/c mouse by improved cell survival and bone marrow engraftment. Yogesh Kumar Verma, Rakesh Pandey, Pawan Kumar Raghav, Gurudutta Gangenahalli. MOLECULAR THERAPY (2022). IF= 10.18
  93. Fabrication and Characterization of a multi-layered scaffold: An approach to repair multiple tissue injury. Tyagi N., Gambhir k., Gangenahalli G., Verma Y K. Bio-fabrication (2026). IF=8.2
  94. Enhancing Cellular Resilience: Synergistic Radioprotection by LiCl and a Novel Bax Antagonist Peptide in Molecular Diversity. Yogesh Kumar Verma, Pawan Raghav, Rakesh Pandey, Gurudutta Gangenahalli. Journal - Molecular Diversity (2026). IF=4.4
  95. GE data published on GEO Omnibus
  96. MSCs - LiCl (2Mm) priming To decipher Osteogenic Transcriptional signaling - Particularly, RunX (Mater TF) upregulated promotes synthesis of BC materials – OC, BSP, O-Pontin, Onectin, Proteoglycan, ALP). ATF4, CLEC, RRAD Vital loop, RRAD formed vital loop. RRAD master Osteogenic–gene (Validated by siRNA). GEO/GSE:34747
  97. APC (Adenomatous polyposis protein) induced anti-sense expression in SaOS2 cells (cloned and generated). To find out APC mediated Wnt activation in Osteogenesis. Set of Adhesion molecules (CDH8, CD44, ICAM1 etc. upregulated (may be supporting in HSC-MSC interaction). Also, Down-regulated p-STAT3. Shown to activate β- catenin activation. GEO/GSE: 78818- NIH, USA
  98. Leukemic Cell (K562) cell treated with Radiation (4 Gy & 8 Gy) & LiCl (2Mm) & BAP (GR23) - To study the radiation response as K562 cells display resistant behavior. CAM, including β-integrin & survival genes upregulated        β-integrin plays a role in CAM-RR.  GEO/GSE: 73486-NIH, USA
  99. SCF-receptor (c-Kit) induced expression in GE D816V & Transfected U937 cells - To identify the down-stream biochemical mechanism of SCF-receptor (c- Kit, a tyrosine Kinase) in SC proliferation.     Several candidate genes promoting proliferation and self- renewal upregulated in GE cells comparing to wt. c-Kit. GEO/GSE:76355- NIH, USA.
  100. CXCR4 (native, Mutant-GE) (N119S) - To identify down- stream CXCR4 signaling - Several clusters analyzed RELN1, identified as a critical target mediating down-stream signaling. GEO/GSE/ 76544- NIH, USA.
  101. Treatment of KG1a cells with LiCl after irradiation on gene expression pattern to study the effect of LiCl, to activate ‘Wnt’ activation in cells (KG1a) cells irradiated with radiation, analyze the effect on survival. Most importantly, the KRTAP10-2, a new gene was detected. Potential role of LiCl for inducing hair regrowth in radiation alopecia and wound healing through Wnt signalling. (GEO/GSE: 73486-NIH, USA)
  102. Stimulation of human hematopoietic CD34+ cells with cytokines. To identify myeloid specific genes by myeloid specific cytokines. Several cluster of genes and new genes whose role in myelopoietic differentiation is not established have been detected. Gene expression of Myeloid cells stimulated with cytokines GEO/GSE/108719-NIH, USA.
  103. Transfection of human hematopoietic CD34+ cells with nanoparticulate form of human stem cell transcription factor PU.1: native and mutated form Y244D. To identify myeloid specific genes by myeloid specific transcription factor PU.1. Several following cluster of genes and new genes whose role in myelopoietic differentiation is not established or have not been detected. KDELC1, TM7SF2, ERCC2, FOXA1, ATF5, MAGEA11, FAM107B, LMNB1. Gene expression of Myeloid cells stimulated with PU.1 and myeloid specific cytokines (IL- 3+GM-CSF+Flt-3+MCSF+SCF). GEO/GSE/108720-NIH, USA.
  104. Human umbilical vein endothelial cells irradiation and to analyze changes in gene expression. To identify selectively, radiation induces what genes in endothelial cells. Several cluster of genes and new genes whose role in radiation response have not been detected. Radiation specific Gene expression in human endothelial cells. GEO/GSE/108723-NIH, USA.
  105. Analysis of genes of Bone-marrow expressed under radiation exposed and protected condition. To identify genes sensitive to radiation. Several cluster of genes and new genes whose role in radiation response have not been detected. Radiation specific Gene expression in human BM endothelial cells. GEO/GSE/108722-NIH, USA.
  • CONFERENCE PRESENTATIONS/ABSTRACTS/PROCEDINGS
  1. Application of Specific Antibodies in the study of cellular UV photo product repair kinetics appears promising. 20Th Meeting of the Federation of European Biochemical Societies (FEBS), Budapest, Hungary, August 19-24th 1990. G U GURUDUTTA, U P S Chuahan, Vinay Jain. INTL. CONFERENCE.
  2. Biochemical Modulation of Cell Energy: Inhibition of UV (254 nm) specific repair process in human peripheral blood lymphocytes. 16Th International Congress of Biochemistry & Molecular Biology, 19-22nd September, 1994. Delhi. G U GURUDUTTA, U P S Chuahan, Ramesh Chandra. INTL. CONFERENCE.
  3. Excision of UV (254 nm) induced cyclobutane thymidine dimer in pheripheral blood lymphocytes: Evaluation by Immunochemical Method. International symposium on Perspectives in Bioorganic Chemistry, 8-9Th Dec 1994, University of Delhi, Delhi. G U GURUDUTTA, U P S Chuahan, Ramesh Chandra. INTL. CONFERENCE.
  4. Potential Tracer Ability of 99mTc-Acetylated-LDL to image sites localized by cells bearing scavenger receptor. Society of Nuclear Medicine Annual Conference, Madurai, 1999. G U GURUDUTTA, A K Babbar and R K Sharma. NATIONAL CONFERENCE.
  5. Effects of DNA ligand Hoechst-33342 on the fidelity of DNA repair of restriction enzymes-induced double strand breaks. International Conference on Radiation Damage and its Modification, 12-15Th Nov 2002, INMAS, Delhi-54. Shailaja Singh, G U GURUDUTTA and T L Mathew. INTL. CONFERENCE.
  6. Stem cell survival enhancement response by BCL-2 structural variants. International Conference on Radiation Damage and its Modification. 12-15Th Nov 2002, INMAS, Delhi-54. G U GURUDUTTA, Yogesh Kumar Verma, Soumya Pati, Vimal Kishore Singh, Pallavi Gupta, Rajat Kumar, H G Raj. INTL. CONFERENCE.
  7. Stem cell factor receptor variants in proliferation responses of hematopoietic stem cells. International Conference on Radiation Damage and its Modification. 12-15Th Nov 2002, INMAS, Delhi-54. G U GURUDUTTA, Soumya Pati, Yogesh Kumar Verma, Soumya Pati, Vimal Kishore Singh, Pallavi Gupta, Rajat Kumar. INTL. CONFERENCE.
  8. 99mTc Labeled Acetylated LDL: A novel tracer for imaging studies of scavenger receptor sites of macrophageal origin. XXIV Annual Conference of Indian Association of Biomedical Scientists “Radiotracers in Drug Development:” 1-4Th Nov, 2003, INMAS (DRDO), Delhi-54. G U GURUDUTTA, A K Babbar, S Shailaja, P, Soumya, R K Sharma. NATIONAL CONFERENCE
  9. Stem Cell Antigen CD34 induced over expression enhances stem and progenitor cell adhesion to stromal cells: Implications for in vivo efficient homing. International Society of Stem Cell Research Meeting held at San Francisco, USA. 2004. Vimal Kishore Singh, GURUDUTTA U GANGENAHALLI, Rakesh Sharma, Ramesh Chandra, Pratibha M Luthra. INTL. CONFERENCE.
  10. Stem Cell Transcription Factor – PU1 (Master commitment Switch) up regulates Myelopoiesis: Effect of Graded Ectopic Expression. International Society of Stem Cell Research Meeting held at San Francisco, USA. 2004. Pahlavi Gupta, GURUDUTTA U GANGENAHALLI, Daman Saluja, Rakesh Sharma, Ramesh Chandra, Ravindranath T. INTL. CONFERENCE.
  11. The human stem cell factor receptor (c-Kit): Molecular simulations of binding of tyrosine dephosphatase – SHP-2. International Symposium of Structural symposium – 2004, 17-21St Nov 2004, Washington (DC), USA. Soumya pathi, GURUDUTTA U Gangenahalli, Rakesh Sharma, Ramesh Chandra, Lazar Mathew. INTL.CONFERENCE.
  12. Development of Countermeasures to protect human hematopoietic CD34+ cells from Low & High LET Radiation. 12th International Congress of Immunology and 4Th Annual Conference of FOCIS, 19-23rd July 2004, Montreal, Quebec, Canada. GURUDUTTA U Gangenahalli, John M Millholand, Anna Kalota, Paula Bennet, Bestty M Sutherland, Anna Gewiritz. INTL. CONFERENCE.
  13. Modification in the induction levels of DNA double strand breaks and nuclear recruitment of repair proteins likely determinants of Radio-protection (Radio-resistance). GURUDUTTA U Gangenahalli, John M Millholand, Anna Kalota, Paula Bennet, Bestty M Sutherland, Anna Gewiritz. 33rd Annual Scientific Meeting of Intl. Society of Experimental Hematology (ISEH-2004).
  14. Countering low-linear energy transfer (LET) and high-LET radiation exposure with pro-methyl Hoechst (PMH) and EUK- 134 (Mg-Salen Complex): Radioprotection of normal and irradiated human bone marrow derived CD34 cells. In a simulated deep space environment. 15Th Human in Space Symposium, Graz / Austria, May 22-26, 2004. GURUDUTTA U Gangenahalli, J.M.Millholland, a Kalota, P Bennet, B.M.Sutherland, Alan Gewirtz. INTL.CONFERENCE.
  15. Protein modeling studies of stem cell factor receptor (c-Kit), the master regulator of downstream signaling events involved in proliferation and differentiation of stem cells. The International Conference on Recent Advances in Biomedical & Therapeutic Sciences (ICRABTS-2004), 13-15Th Jan, Bundelkhand University, Jhansi, India. G U GURUDUTTA, Soumya Pati, Vimal Kumar Singh, Yogesh Verma, Pallavi Gupta, Rajat Kumar, R K Sharma and Lazar Marhews. INTL. CONFERENCE.
  16. Contributions of differentiation factor PU.1 in cell fate decisions of hematopoietic stem cells. Indo-Tunisian Workshop on Bio-Technology in Medicine. 28-29Th June 2004, INMAS (DRDO), Delhi. G U GURUDUTTA, P Gupta, Yogesh Verma, Soumya Pati, Vimal Kishore Singh, Rajat Kumar, Daman Saluja and R K Sharma. REGIONALCONFRENCE.
  17. Structural analysis of stem cell factor receptor (c-kit) for prediction of functional variants that can enhance proliferation potential of stem cells in in-vitro. NCBS (National Center for Biological Sciences) Symposium on Molecules, Machines and Networks. 5-9Th Jan 2004. G U GURUDUTTA, Soumya Pati, Vimal Kumar Singh, Yogesh Verma, Pallavi Gupta, Rajat Kumar, R K Sharma and Lazar Mathews. NATIONAL CONFERENCE.
  18. Structural identification of functional residues in antiapoptotic protein BCL-2. International Conference on Recent Advances in Bio-Medical & Therapeutic Sciences, 13-15Th Jan 2004, Bundelkhand University, Jhansi, India. G U GURUDUTTA, Yogesh Verma, Soumya Pati, Vimal Kishore Singh, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj and R K Sharma. INTL. CONFERENCE.
  19. Sequence and Structural analysis of hematopoietic transcription factor PU.1: Implications in Differentiation responses of stem cells. International Conference on Recent Advances in Bio-Medical & Therapeutic Sciences, 13-15Th Jan 2004, Bundelkhand University, Jhansi, India. G U GURUDUTTA, Yogesh Verma, Soumya Pati, Vimal Kishore Singh, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj and R K Sharma. INTL. CONFERENCE.
  20. Structural identification of functional residues in antiapoptotic protein BCL-2. International Conference on Recent Advances in Bio-Medical & Therapeutic Sciences, 13-15Th Jan 2004, Bundelkhand University, Jhansi, India. G U GURUDUTTA, Yogesh Verma, Soumya Pati, Vimal Kishore Singh, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj and R K Sharma. INTL. CONFERENCE.
  21. Sequence-to-Sequence –to-function analysis of hematopietic stem cell marker CD34 for the indentification of functionally important residues. International Conference on Recent Advances in Bio-Medical & Therapeutic Sciences, 13-15Th Jan 2004, Bundelkhand University, Jhansi, India. G U GURUDUTTA, Vimal Kishore Singh, Yogesh Verma, Soumya Pati, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj and R K Sharma. INTL. CONFERENCE.
  22. The CD34-antigen molecular domains implied in potential homing and engraftment of hematopoietic progenitors. 7Th Annual meeting of American Gene-Therapy, 2-6Th June, 2004, Minneapolis, USA. G U GURUDUTTA, Vimal Kishore Singh, Soumya Pati, Yogesh Verma, Pallavi Gupta, R K Sharma, Ramesh Chandra, Rajat Kumar, Pratibha Mehta Luthra. NATIONAL CONFERENCE.
  23. Determination of SH3 domain binding site in the hematopoietic stem cell marker CD34. Indo-Tunisian Workshop on Bio- Technology in Medicine. 28-29Th June 2004, INMAS (DRDO), Delhi. G U GURUDUTTA, Vimal Kishore Singh, Soumya Pati, Yogesh Verma, Pallavi Gupta, R K Sharma, Ramesh Chandra, Rajat Kumar, Pratibha Mehta Luthra. REGIONAL WORSHOP/CONFERENCE.
  24. Molecular simulation of structural events involved in switching signals (Off/On) in stem cell proliferation by stem cell factor receptor (C-KIT) interactions. Indo-Tunisian Workshop on Bio-Technology in Medicine. 28-29Th June 2004, INMAS (DRDO), Delhi. G U GURUDUTTA, S Pati, VK Singh, Y Verma, P Gupta, Rajat Kumar, R K Sharma. REGIONAL WORSHOP/CONFERENCE.
  25. Stem cell fate specification by master regulatory switch driving differential hematopoiesis: Transcription Factor PU.1. International Symposium on “Chemistry-Biology Interface Synergistic New Frontiers. 21-26Th, Nov 2004, New Delhi, India (Organized by Dr.Ambedkar Center for Bio-Medical sciences, University of Delhi, Delhi-110007). Pallavi Gupta, G U GURUDUTTA, Daman Saluja, T Ravindranath, Yogesh Verma, Pallavi Gupta, R K Sharma, Ramesh Chandra, R K Sharma. INTL. CONFERENCE.
  26. Homology Modeling of Anti-Apoptotic Protein BCL-2. International Symposium on “Chemistry-Biology Interface Synergistic New Frontiers. 21-26Th, Nov 2004, New Delhi, India (Organized by Dr.Ambedkar Center for Bio-Medical sciences, University of Delhi, Delhi-110007). G U GURUDUTTA, Yogesh Verma, Vimal Kishore Singh, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj, R K Sharma. INTL. CONFERENCE
  27. Structural Conservation of BH1 & BH2 and BH2 Domains in BCL-2 Family of Proteins. International Symposium on “Chemistry- Biology Interface Synergistic New Frontiers. 21-26Th, Nov 2004, New Delhi, India (Organized by Dr.Ambedkar Center for Bio-Medical sciences, University of Delhi, Delhi-110007). G U GURUDUTTA, Yogesh Verma, Vimal Kishore Singh, Pallavi Gupta, Ramesh Chandra, Rajat Kumar, H G Raj, R K Sharma. INTL. CONFERENCE.
  28. Stem Cell Antigen the CD34: Its possible structure based functional implications relevant to migration & homing of transfused stem cells to bone marrow. International Symposium on “Chemistry-Biology Interface Synergistic New Frontiers. 21- 26Th, Nov 2004, New Delhi, India (Organized by Dr.Ambedkar Center for Bio-Medical sciences, University of Delhi, Delhi-110007). G U GURUDUTTA, Vimal Kishore Singh, Yogesh Verma, Pallavi Gupta, R K Sharma, Ramesh Chandra, Rajat Kumar, Pratibha Mehta Luthra. INTL. CONFERENCE.
  29. Stem Cell Transcription factor PU.1: The identification of residues critical for its functional interactions with GATA-1 during hematopoietic lineage commitment. International Symposium on Stem Cells: From Laboratory to Treatment of Diseases. 27-28Th Dec 2005. IMGENEX India Pvt Ltd. E-5, Infocity, Bhubaneswar. G U GURUDUTTA, Pallavi Gupta, Yogesh Verma, Vimal Kishore Singh, Ramesh Chandra, R K Sharma and Daman Saluja. INTL. CONFERENCE.
  30. Hematopoietic stem cell survival enhancement by controlled induction of genetically engineered BCL-2 molecule. International Symposium on Stem Cells: From Laboratory to Treatment of Diseases. 27-28Th Dec 2005. IMGENEX India Pvt Ltd. E-5, Infocity, Bhubaneswar. G U GURUDUTTA, Pallavi Gupta, Yogesh Verma, Vimal Kishore Singh, Ramesh Chandra, R K Sharma and Daman Saluja. INTL. CONFERENCE.
  31. Stem cell differentiation control by transcription factor PU.1: Potential effects of its native & engineered forms in human bone marrow CD34+ cells. First Annual Meeting of Stem Cell Research Forum of India (SCRFI) and International Conference of Stem Cell Research, Bangalore (Oral Presentation), 2007. G U GURUDUTTA & Pallavi Gupta. NATIONAL CONFERENCE.
  32. Stem Cell Therapeutic Potential Enhancement through Genetic Engineering as Applicable to Bone Marrow Transplantation to Treat Radiation Injury at Biotechnology Society of India 12th Foundation Day Symposium “Molecular Medicine-the emerging frontiers” organized by the Department of Biotechnology & Molecular Medicine, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak on 9th January, 2008. Yogesh Verma & G U GURUDUTTA. REGIONAL CONFERENCE.
  33. Modulation of Homing/Engraftment Potential of Hematopoietic Syem Cell Antigen CD34, International Symposium on Model Organism and Stem Cells in Development, Regeneration and Disease at National Centre for Biological Sciences, TIFR, Bangalore, India, 23rd-25th February 2008. Vimal K Singh & G U GURUDUTTA. INTL. CONFERENCE.
  34. Hematopoietic Stem Cells Survival Enhancement Through Induced Over-Expression of Bcl-2 Mutants for Radio-Protection, International Symposium on Model Organism and Stem Cells in Development, Regeneration and Disease at National Centre for Biological Sciences, TIFR, Bangalore, India, 23-25th February 2008. Yogesh Verma & G U GURUDUTTA. INTL. CONFERENCE.
  35. Hematopoietic stem cell antigen CD34: Role in adhesion or homing. International Symposium on Model Organisms and Stem Cells in Development, Regeneration and Disease Held at National Centre for Biological Research, TIFR, Bangalore, India, from 23-25th Feb, 2008. Vimal K Singh & G U GURUDUTTA. INTL. CONFERENCE.
  36. Docking of anti-apoptotic protein Bcl-2 with its antagonists for radiation injury management” in International conference on open source computer aided drug design, IMTECH, Chandigarh, India, 22- 26th March 2009. Pawan Raghav, Yogesh Verma & G U GURUDUTTA. INTL. CONFERENCE.
  37. Stem cell response control through genetic engineering of critical genes with gain-of-function mutations as relevant to enhancement of their utility potential in transplantation for acute radiation syndrome. GURUDUTTA GANGENAHALLI. International Meeting of the Stem Cell research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  38. Hematopoietic stem cells: molecular regulation and proliferation using stem cell specific gene c-kit. (Poster Presentation). Shilpa Sharma, G U GURUDUTTA, Farhat Afrin. International Meeting of the Stem Cell Research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  39. Stem cell homing and engraftment up-modulation through genetic engineering of SDF-1 /CXCRF4 axis (Poster Presentation). Menka Sharma, Pwan Kumar Raghav, Farhat Afrin, G U GURUDUTTA. Iinternational Meeting of the Stem Cell Research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  40. Mesenchymal stem cell: activation of Wnt signaling initiates priming towards osteogenic lineage. (Poster Presentation). Neeraj Kumar Satija, G U GURUDUTTA and Farhat Afrin. International Meeting of the Stem Cell Research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  41. Stem cell antigen CD34 mediated adhesion signaling is regulated through CRKL-L-interaction. (Poster Presentation). I Vimal Kishor Singh & GURUDUTTA GANGENAHALLI. International Meeting of the Stem Cell Research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  42. Stem cell shielding by Nano-organized polymer response assessment. (Poster Presentation). Siddhartha Pandey, G U GURUDUTTA, Fahrat Afrin. International Meeting of the Stem Cell API-III-E-iia (Meeting was cancelled at the last moment, included for API.) research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  43. Site-directed variants of Bcl-2 (D34A and S70E) augment irradiated and serum deprived hematopoietic cells survival: Implication in stem cell transplantation. (Poster Presentation). Yogesh Kumar Verma, Pawan Kumar Raghav, GURUDUTTA GANGENAHALLI, International Meeting of the Stem Cell Research Forum of India, Bangalore, 8- 10Th Feb 2011. INTL. CONFERENCE.
  44. Stem cell transplantation factor PU.1 with mutated β3/β4 domain selectively elicits myeloid differentiation: potential implications in Inducible differentiation therapy. Pallavi Gupta, GURUDUTTA GANGENAHALLI, Daman Saluja and Jyoti Zack. International Meeting of the Stem Cell Research Forum of India, Bangalore, 8-10Th Feb 2011. INTL. CONFERENCE.
  45. Genetically engineered BCL-2 functional variants over-expression induces radio resistance in Hematopoietic cells. GURUDUTTA GANGENAHALLI *, Yogesh Kr verma, Pawan Kumar Verma, Raghav, H G Raj. International Conference on Radiation Biology, Nano-technology & Imaging, Stem Cell Research (Indian Society of Radiation Biology). Nov 15-17th. 2010. Chennai. INTL. CONFERENCE.
  46. Mesenchymal stem cell: Activation of Wnt signaling initiates priming towards osteogenic lineage. Neeraj Kumar Satija, Farhat Afrin & GURUDUTTA GANGENAHALLI. 2nd International Conference on Stem Cells and Cancer, Pune. October 15-18th, 2011. INTL. CONFERENCE.
  47. Stem cell shielding by nano-organized polymer, response assessment. Siddharth Pandey, GURUDUTTA GANGENAHALLI & Farhat Afrin. 2nd International Conference on Stem Cells & Cancer. Pune. October, 15-18th, 2011. INTL. CONFERENCE.
  48. In Silico Analysis of Flexible Loop Domain’s Conformational Changes Affecting BH3 Cleft of Bcl-2 Protein. Pawan Kumar Raghav, Yogesh Kumar Verma, GURUDUTTA GANGENAHALLI. International Interdisciplinary Science Conference. Jamia Milia Islamia. Delhi. Nov xxth 2011 (Journal of Natural Science, Biology and Medicine" volume 2, issue 2, 2011). INTL. CONFERENCE.
  49. Current advances in Biotechnology and Medicine, 24-25th Feb, 2012. GURUDUTTA GANGENAHALLI, Institute of liver and biliary sciences (ILBS), New Delhi. INTL. CONFERENCE.
  50. Computational network model predicts the drug effects on SHP-1 mediated intracellular signaling through c-Kit. Alisha Praveen, Pawan Kumar Raghav, Gurudutta U Gangenahalli. Journal of Proteins and Proteomics. ISSN:0975-8151; 3(2).9. 2012. INTL. CONFERENCE.
  51. Synthesis and characterization of super-paramagnetic Dextran-coated iron oxide nanoparticles and in vivo application in resonance imaging. Sushant Kumar Mishra, G U Gurudutta, Subhas Khushu. International conference and workshop on Nano-structured ceremics and other nano-particles (ICWNCN-2012). March 13-16th, 2012, University of Delhi, Delhi. INTL. CONFERENCE.
  52. Adhesion or anti-adhesion? What is the significance of stem cell antigen CD34 in hematopietic biology?. Vimal kishore Singh, Ramesh Chandra, Gurudutta Ugraiah Gangenahalli, Murali Dhar Tiwari. Native and Induced Pluripotent Stem Cell Standardization. March 19-21th, 2012, RIVER PUBLISHERS, Florence, Italy. INTL. CONFERENCE
  53. Adenomatous Polyposis Coli: A Potential Target for Studying the Wnt Signaling. Neeraj Kumar Satija and Gurudutta Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  54. Efficient Tracking of Labeled Mesenchymal Stem Cells in Traumatic Brain Injury of Mice through Magnetic Resonance Imaging. Sushanta Kumar Mishra, G.U.Gurudutta, R.P.Tripathi and Subash Khushu. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  55. Osteoconductive composite scaffolds significance for bone tissue engineering application. Deepa Sharma, Neeraj Satija , Siddharth Pandey and Gurudutta Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC- 2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  56. High throughput transcriptome profile reveals synergistic pleiotropic mechanisms of activated stem cell factor receptor of stem cells. Shilpa Sharma, Farhat Afrin, Gurudutta Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  57. Target Identification and Drug Designing Inhibits Phosphatase Activity of PTPases: A Pharmacophore Based Study Increases Stem Cell Proliferation. Pawan Kumar Raghav, Shilpa Sharma, Gurudutta U Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  58. Stem Cell Regulation of Myelopoiesis by PU.1 Mutants: Virtual Screening of PU.1 Peptides with C-Jun and GATA-1. Pawan Kumar Raghav, Pallavi Gupta, Gurudutta U Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  59. Stem cells from origin to death. Pawan Kumar Raghav, Yogesh Kumar Verma, Gurudutta U Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL.  CONFERENCE.
  60. Stem Cell Transmigration: Efforts to elucidate the support of transmigration by human endothelial cells exposed to radiation its mechanistic insight. Siddharth Pandey, Farhat Afrin and Gurudutta Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 to Oct 30th, 2012 at PGIMER Auditorium, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India. INTL. CONFERENCE.
  61. Synergism in reducing apoptosis as derived from response of Bcl2 mutant’s expression and LiCl treatment. Yogesh Kumar Verma and Gurudutta Gangenahalli. 3rd International Conference on Stem Cells and Cancer (ICSCC-2012): Proliferation, Differentiation and Apoptosis, scheduled from Oct 27th, 2012 
  62. (From 62-104 could not be uploaded due to limitation of space)

BOOKS/BOOK CHAPTERS (IF ANY)

  1. *GURUDUTTA G U* et al. Stem cell therapeutic potential enhancement through genetic engineering as applicable to bone marrow transplantation to treat radiation injury. BIOTECHNOLOGY SOCEITY NEWS LETTER. 2008. (* Corresponding Author).
  2. *GURUDUTTA G U* et al. Stem cells as potential targets for hematopoietic gene transfer: An Over view. BIO-TECHNOLOGY IN HEALTH CARE (Eds:T Lazar Mathew), INMAS, Delhi, 2001. (*Corresponding Author).
  3. Rajesh Aurora, Raman Chawala, GURUDUTTA G U et al. Bio-prospection for Radioprotective Molecule from Indigenous Flora. Chapter-9: Recent Progress in Medicinal Plants. Vo.16 (Editor: J N Govil). Stadium Press. LLC. Houstan. USA. P179-219.2006.
  4. *Swathi Sharma, Uppma Singh & Gurudutta Gangenahalli*. Stem cell origins of cytokine interactions (Nov Medicine & Health, New York). Editor: Prasad Koka. Chapter-16. Stem Cell Genes Synergism. 2018.
  5. *Sushant Mishra, Subhas Kushu & Gurudutta Gangenahalli*. A Distinctive MRI-Based Absolute Bias Correction Protocol for the Potential Labelling and In Vivo Tracking of Stem Cells in a TBI Mice Model. Methods in Molecular Biology. DOI 10.1007/7651_2019_277 2 © Springer Science + Business Media New York 2019.
  6. Computational methods (in silico) and stem cells as alternatives to animals in research. Nishant Tyagi, Subodh Kumar, Gurudutta Gangenahalli, Yogesh Kumar Verma*. Cheminformatics and Bioinformatics in the Pharmaceutical Sciences. 389-421. May 2021. Academic Press (New York). (Editors: Navneet Sharma Himanshu Ojha Pawan Raghav Ramesh K. Goyal).
  7. Reactive Oxygen Species in Stem Cell Proliferation and Cancer. Verma Y.K., Kumar S., Tyagi N., Gangenahalli G. (2021).  In: Chakraborti S., Ray B.K., Roychowdhury S. (eds) Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-15-4501- 6_118-1.
  8. The impact of Mindfulness, yoga on Neurocognitive, Neurophysiological and Neuropsychological changes in high altitude. Gurudutta Gangenahalli, Vikas Chander, Yogesh Kumar Verma and Shweta Singh. Neuroscience of Yoga (Springer-Nature). 2022

PATENTS (IF ANY)

           Dr. Gurudutta Gangenahalli as Principal Investigator/Main inventor

  1. A method of single cell encapsulation and uses there-off (Liposomes). Filed Patent Number: 2442/DEL/2014 (Indian patent). PATENT AWARDED-326745/IPO
  2. A method of preparing a multi-layer encapsulated cell population and uses there-off (Alginate-Fbn Conjugate). Filed Patent Number: 2159/DEL/2015 (Indian patent). PATENT AWARDED-338569/IPO
  3. A method of preparing a multi-layer encapsulated cell population and uses there-off (Alginate+Chitosan LbL). Filed Patent Number: 2158/DEL/2015 (Indian patent) PATENT AWARDED-337135/IPO
  4. Compositions for Hemostasis and Wound healing, and Implementation thereof (Formulations for hemostasis and wound healing at high altitudes based on the combined potential of poloxamer407, alginate, LiCl and serum). Filed Patent Number. DEL No. 201811022395. PATENT AWARDED-432172/IPO
  5. Process and Composition for coating cells and uses thereof. (For a novel method for effective delivery of human hematopoietic stem cells by using Poloxamer-407 as bone-marrow specific targeting agent for its complete regeneration). Filed Patent Number: Del No: 201711033030. PATENT AWARDED-462959/IPO
  6. Encapsulated biocomponent and Implementations thereof (Anti VCAM-1 peptide polymer conjugate as Bone Marrow vascular sinusoidal targeting agent. PATENT AWARDED-523119/IPO
  7. A novel Bax antagonist peptide (BAP) in conjunction with LiCl for decreasing cellular radiation injury. Filed Patent Number: DEL/201611006832. PATENT AWARDED-551356/IPO
  8. Competitive dys-regulation of PU.1 with GATA-1 by a novel PU.1 peptide analog a potential drug like molecule selectively enhances myelopoiesis. Filed Patent DEL No. 202011045773
  9. A novel formulation to rescue radiation induced death by combination of LiCl, Bax antagonist peptide (GR23) and ascorbic acid. Filed Patent DEL No. 202111027432.
  10. Amine functionalized alginate as novel gene transfection agent. PATENT AWARDED - 595369IPO (Dt of Award: 14/7/2026).
  11. Bi-layered scaffold with drug delivery system for repair of complex tissue injuries and methods thereof. Application No-202611031390 (DRDO REF. No. ERIP/IP/2401058/M/01).
  12. A formulation containing Poloxamer 188, ATP and MgCl2 to provide protection to irradiated cells. Patent filed. (Note: DRDO don’t permit patenting abroad).

HONOURS AND AWARDS (IF ANY)

AWARDS

  • Defence (DRDO) - Scientist of the Year Award – 2017, Min. of Defence, DRDO, Govt. of India
  • DRDO - Lab Technology Development Group Award-2005. Min. of Defence, DRDO, Govt. of India
  • DRDO - Defence Technology Day Award - 2010  Min. of Defence, DRDO, Govt. of India
  • DRDO - Laboratory Scientist of the Year – 2011   Research & Development Organization, Min. of Defence.
  • Anubhav Award-2020 (Awarded to select Civil Servants of the Govt. of India (including IAS, IPS etc. 5 awards/year). MOPT. Govt. of India
  • Certificate Awarded for Providing Instructional and Training Support to 1St Molecular Medicine Winter School 9Th Feb 8-28Th 2010 “Gene to Disease”. Department of Biotechnology & Molecular Medicine POST-GRADUATE Institute of Medical Sciences, Pt. Bhagwat Dayal Sharma University of Health Sciences, Rohtak By Vice- Chancellor.
  • Certificate Awarded in appreciation of the contribution made in the conduct of exhibition on “Science in the Service of Soldgier” 1991
  • ICMR - Travel Grant for Abroad 2018 - ICMR travel grant was awarded to attend 20th International Conference on Stem Cells and Regenerative Medicine, February 15 - 16, 2018, held in London, United-Kingdom
  • Conference Awards (5)

HONOURS 

  • Post-Doctoral Fellowships (FAPESP, Brazil; NASA / NSBRI, USA, NRC (Canada)
  • Elected to  several Academy Fellowships
  • Editorial Board Member several prestigious journals
  • Prestigious International Program Advisory Committee of DST. GoI. Member >12 years 

REVIEWING AND EDITORIAL ASSIGNMENT

  • Reviewer- Frontiers in Biosciences, USA
  • Reviewer- Stem Cell & Development, USA
  • Reviewer - Molecular Endocrinology, USA
  • Reviewer- Stem Cells (Translational Medicine) USA)
  • Reviewer – Journal of Transplantation, USA
  • Reviewer – Indian Journal Medical Research, India
  • Reviewer – Circulation, Japan
  • Reviewer – Defence Science Journal, Defence Research & Development Organization, Govt of India, India
  • Reviewer - Stem Cells (Translational Medicine) (USA)
  • Reviewer- Cell Proliferation (Springer)
  • Reviewer- Journal of Chemical Biology
  • Reviewer- Journal of Molecular Medicine
  • Reviewer- Stem Cells (Alpha-med, USA)
  • Reviewer- Bio-Med Research International (Hindawi Publishing Corporation)
  • Reviewer- Nano

EDITORIAL BOARD

  • Senior Editor, EIC- Integrative Medicine Case Reports (IMCR)
  • Editor, Journal of Transplantation & Stem Cell Biology
  • Editor, World Journal of Stem Cells. China/USA
  • Editor, World Journal of Biological Chemistry
  • Editorial - Annals of Neurology, India
  • Editor - World Journal of Haematology
  • Editor - Journal of Musculoskeletal disorders, USA

EDITORIAL / REVIEWERS ASSIGNMENT

  • Advancements in hematopoietic stem cell proliferation and self-renewal maintenance. Editorial. Front Cell Dev Biol.2025 Jul 7:13:1607145.
  • Organ-chip-on-a-Chip: An Alternative to Animal Studies in Translational Research. Editor. Elsevier (2026) 

SPONSORED/CONSULTANCY PROJECTS

  • Modification of radiation response in tumor & normal tissues. As Co-investigator. R&D Project INM/263 DRDO. Major Project: 18.06 lacs. May 1993 
  • asic and clinical studies with radio- modifiers for improving of cancer. As Co-investigator R&DProject, INM/280 DRDO. Major Project: 280 lacs. Dec 2002   .
  • Preparation of Technetium-99m Labeled native and oxidized-LDL, and its evaluation for Scintigraphy and therapeutic Intervention of proliferating endothelial smooth muscle cells causing restenosis and atherosclerotic plaques in animal models. As Principal Investigator. R&D Task Project DRDO/Tc.2519/INM/01-99. Minor/Tsk Project: 9.75 lacs. March 1999.
  • Development of pseudo-virion Plasmid mediated in vitro / in vivo gene transfection technology for gene therapy of human stem cell expansion to reconstitute bone marrow. As Principal Investigator: Major R&D Project: DRDO, Govt. of India INM/290. 25 lacs. November 2004.
  • To investigate the cellular consequences of exposing human hematopoietic stem cells to a high-LET (including low-LET) environment that stimulates the radiation environment of deep space & To examine the molecular consequences of exposing human hematopoietic stem cells to a high-LET environment that stimulates the radiation environment of deep -space. (NASA/ NSBRI/ USA/ 066/ 2006).  As Co-investigator Investigator. $400K.
  • Study of stem cell proliferation. Adhesion and differentiation abilities. As principal Investigator DRDO/ INMAS.Govt. of India INM/2519/12/05. Task/Exploratory Project: 7.75 lacs. Nov 2007.
  • Development of stem cells specific micro-encapsulation formulation & devices for insulation of human stem cells to radiation victim to protect & manage radiation injury. As Principal Investigator. DRDO. INM/1.6 of ST-P1-2008/INM- 311. Major Project: 2.9 Crores.
  • Stem cell therapeutics for soldier -To harness multi-tissue potentiality of stem cells (MSCs, HSCs, IPS) to conduct mechanistic studies & to develop products to enhance regenerative responses of stem cells for effectively re-growing / repairing tissues damaged by WAR events (Radiation & Blast injuries). As Principal Investigator & project Director DRDO/INMAS/TC/251 9/2018. April 2018. Major Project: 1.86 crores.

START-UPS (IF ANY)

MOOC COURSES DEVELOPED (IF ANY)

PROFESSIONAL DEVELOPMENT

Professional Scientific courses attended

  • Cell culture: Human Lymphocyte isolation & culturing. 22nd July – 5th Aug 1985. National Institute of Virology, Pune, India
  • Radioimmunoassay: Principles & Applications. 1986. Molecular Endocrinology, Dept. of Biochemistry Indian Institute of Sciences (IISc), Bangalore, India
  • Fluorescence Techniques in Biological Research 24-28th Feb 2003    Institute of Nuclear Medicine & Allied sciences (INMAS), DRDO, Delhi-54, India
  • Environment Health & Radiation Safety (EHRS)  4Th June 2003        Dept. of EHRS, University of Pennsylvania, USA
  • Flow-Cytometry & Cell Sorting. 11Th June 2003.  Dept. of Pathology, University of Pennsylvania, USA
  • Training on Use of Laboratory Animals. 24Th June 2003.Dept. of Laboratory Medicine, University of Pennsylvania, Philadelphia, USA
  • Radiation Safety Training (EHRS). 3rd Sept 2003 Dept. of EHRS, University of Pennsylvania, USA
  • Cs137 (Caesium gamma source) Irradiation User-Facility Training. 5Th Sept 2003. Dept. of Laboratory Medicine,
  • University of Pennsylvania, Philadelphia, USAHIPPA Training. 3rd Sept 2003. Health Insurance Privacy Act, USA
  • Indo-US workshop on “Medical-Countermeasures for Radiation Injury: Current & Evolving Technologies”. 17Th - 20Th August 2008. Institute of Nuclear Medicine & Allied sciences (INMAS), DRDO, Delhi- 54 & NIA&ID, Bethesda, USA.

Professional Administrative courses attended

  • Defense Institute/Academy of Technology Management, Govt. of India, Mussorie. Nov, 2002. Project - Technology Forecasting.
  • Defense Institute/Academy of Technology Management & INMAS Joint CEP Course INMAS, Delhi. March 9Th – 12Th 2006. Building Scientists as Effective Managers.
  • Engineering Staff College of India (ESI), Hyderabad. June 21st – 25th 2010. Technology management for R&D based organization.
  • Indian Institute of Management (IIM), Kazikode, Kerala. July 9th – 11th 2013. Strategic & Change Management
  • Defense Institute/Academy of Technology Management, Govt. of India, Mussorie. May 28th – 30Th 2017. Organizational Behavior.
  • Netaji Subhas University of Technology, Dwaraka, New Delhi. July 26th – 28th 2023. NACC University Accreditation.

ADVISEES

Research Guidance

  • PhDs (Total scholars supervised-24),

  • MPhils -7

  • Post-doctoral -8

  • MTech, MSc, MD, BTech-40

  • Young Scientists -2

  • BTech, MTech projects -10.

  • Trainees: >100

ANY OTHER INFORMATION

Other Professional Achivements

New methods developed

  • Biomaterial based stem encapsulation and targeting formulations.
  • Site directed mutagenesis of human stem cell genes.
  • Expedited wound healing method

New molecules developed

  • Encapsulation biomaterial formulations.
  • Novel Bax antagonist.
  • Myeloid cell enhancing protein nano-mimetic.
  • SHP1 inhibitor for stem cell proliferation.
  • Myeloid cell enhancing peptide mimetics.
  • Stem cell targeting formulations
  • Wound healing formulations
  • Cell sealing and protective formulations
  • Human-LDL pure isolated molecule) as tracer / probe for imaging atherosclerotic & inflammation lesion imaging after labeling with radio-isotope (clinically usable) 99mTc (half- life in vivo 6 hr), where LDL-receptor bearing Macrophages accumulate.
  • Optimize the adjuvant potential of 2-deoxy Glucose (a Glucose analogue) in cancer radiotherapy which is presently in clinical use (for the treatment of human-gliomas).

Category of materials developed as formulations or products:

  • Cell Product: In vitro primed Mesenchymal stem cells as potential osteogenic precursors.
  • Liposome Formulation: Liposomes optimized for single cell encapsulation, specific separation process and targeting for endothelial cells.
  • Alginate Formulation: As nano-particles, characterized for stem cell shielding.
  • Engineered Genes or Proteins: BCL-2, PU.1, CXCR4.

Genetically-modified stable transfectant cells were developed for research purposes:

  • RPMI-82226 (wt-BCL-2 in tet-on plasmid)
  • RPMI-8226 (mut1 BCL-2 in tet-on plasmid)
  • RPMI-8226 (mut2 BCL-2 in tet-on plasmid)
  • Jurkat (wt PU.1 in tet-on plasmid)
  • Jurkat (mut1 PU.1 in tet-on plasmid)
  • Jurkat (mut2 PU.1 in tet-on plasmid)
  • Jurkat (mut3 PU.1 in tet-on plasmid)
  • Jurkat (mut4 PU.1 in tet-on plasmid)
  • Jurkat (mut45PU.1 in tet-on plasmid)
  • U (937) (wt c-Kit in Tet-off plasmid)
  • U (937) (mut1 c-Kit in Tet-off plasmid)
  • K(562) (wt CXCR4 in Tet-on plasmid)
  • K(562) (mut1 CXCR4 in Tet-on plasmid)
  • K(562) (mut2 CXCR4 in Tet-on plasmid)
  • SaOS2 (wt Osterix in Tet-on plasmid)
  • FOX01 (wt)
  • GATA (wt in Tet-on plasmid)
  • GATA (Mt in Tet-on plasmid)