B.E. (Bio-technology): I Year: II Semester
Examination Theory L T P
Paper I BT lll Introduction to Biotechnology 3 1 0
Introduction and scope of Biotechnology — historical perspectives, Biotechnology as an integrated discipline, its applications, future directions.
Introduction to general biology — cell as unit of living matter, living systems :
organization and function, living systems as a source for biomaterials.
Basic concepts of molecular biology - Gene Structure, function and organization.
Concept of Gene manipulation.
Biological variation — mutation, recombination and adaptation. The concept of
evolution.
Commercial applications — Biotechnology in Industry, food, agriculture and healthcare.
Ethical and regulatory issues.
Reading materials
1. Agriscience and Technology by B.L. DeVere. Publisher : Delmar Publishers.
2. Agriscience Fundamentals and Applications by Walter and York. Publisher :
Delmar Publishers.
3. Biotechnology Unzipped by E.S. Grace. Publisher: Joseph Henry Press/ National
Academy Press.
4. Biotechnology: An Introduction by S.R.Bamum. Publisher:Wadsworth Publishing
Company.
5. Biotechnology-Demystifying the Concepts by D.Bourgaize, T.R. Jewell and R.G.
Buiser. Publisher : Addison-Wesley Longman.
6. Eighth Day of Creation 1 Makers of the Revolution in Biology by H.F. Judson.
Publisher : Cold Spring Harbor Laboratory.
7. In Praise of Imperfection by R.L. Montalcini. Publisher : Basic Books.
8. Molecular Biology of the Gene by J .D. Watson and J. Steitz. Publisher : Addison-
Wesley Publishing.
9. Principles of Biotechnology -
http ://wwwbiotcch.iastate.edu/biotcch_info_scrics/bio l .html
10. The Double Helix : A Personal Account of the Discovery of the Structure of DNA
by J .D. Watson. Publisher: Touchstone Books.
ll. The Lives of a Cell : Notes of a biology watcher by L. Thomas. Publisher :
Penguin USA.
12. The Science of Agriculture, A Biological Approach. by R.V. Herren. Publisher :
Delmar Publishers.
13. Biology by K.R. Miller and J . Levine. Publisher : Prentice Hall.
14. Understanding DNA and Gene Cloning by K. Drlica. Publisher : Wiley and Sons
Company.
B.E. (Bio-technology): I Year: II Semester
Examination Theory L T P
Paper II BT 112 Physics II 3 1 0
Quantum Mechanics: Matter Waves and de- Broglie Hypothesis, Uncertainty
Principle, Wave packets, Schroedinger`s wave equation, Interpretatation of wave
function, Simple Eigen value problems and degeneracy.
Metallic Conductors: Fenni electron model, Energy distribution, Fenni energy, Fenni-
Dirac probability function, Fermi level, Conduction process, effect of temperatures and
impurities.
Semiconductor : Band Theory of Solids, types of semiconductors, statistics of holes
and electrons, Hall effect, Effect of temperature on conductivity, life time and
recombination , drift and diffusion , p-n junction.
Superconductors: Types of super conductors, Meissner effect, Josephson effect, High
temperature superconductors.
Dielectric and Magnetic Materials: Polarization of dielectric and its break down.
Piezoelectricity, Ferroelectricity, Electrets, Ceramic; Dia, Para, Ferro-magnetism
Laser : Principle, Einstein’s A and B coefficients, He—Ne LASER, Semiconductor
LASER, Applications.
Statistical Physics: Maxwell classical distribution law, degree of freedom and law of
equipartition of energy, mean free path. Quantum statistics: Fermi-Dirac and Bose-
Einstein distribution, fermi-Dirac probability function fenni—level.
Nuclear Physics: Structure of nucleus, binding energy, nuclear models, discovery of
neutrons, particle detectors and accelerators, artificial radioactivity, fission and fusion,
nuclear reactors.
Radiation physics : Elements of radioactivity, dosimetry, radiation hazards on
biosystems and the remedies, applications of radioactivity in biosystems.
Reading materials
l. Advances in Statistical Physics of Solids and Liquids by S. Prakash.
Publisher : New Age International.
2. College Practical Physics by D.R. Khanna and H.R. Gulati. Publisher : R.
Chand and Company.
3. Elements of Properties of Matter by D.S. Mathur. Publisher : S. Chand and
Company.
4. Fundamentals of Optics by D.R. Khanna and H.R. Gulati. Publisher : R.
Chand and Company.
5. Introduction to Solid State Physics: A Short Course by C. Kittel. Publisher:
John Wiley and Sons Inc.
6. Introduction to Special Relativity by R. Resnick. Publisher : John Wiley and
Sons Inc.
7. Introductory Nuclear Physics by K.S. Krane. Publisher : John Wiley and
Sons Inc.
8. Laser by R.S. Sirohi. Publisher : New Age International.
9. Physics by A. Beiser. Publisher: Addison-Wesley Publishing.
l0. Physics by R. Resnick and D. I-Ialliday. Publisher : John Wiley and Sons Inc.
ll. Quantum Mechanics by B. Crasemann and J.L.Powell. Publisher : Addison-
Wesley Publishing.
l2. Solid State Physics by S.O. Pillai. Publisher : New Age Intemational.
13. Waves and Oscillation by B.L. Subrahmanyam. Publisher : Vikas Publishing
House.
B.E. (Bio-technology) I Year II Semester
Examination Theory L T P
Paper III BT 113 Chemistry II 3 1 0
Reaction mechanisms — Nucleophilic and electrophilic aliphatic and aromatic
substitution reactions, elimination reactions, inductive effect, electromeric effect,
mesomeric effect, hyperconjugation
Reaction Intermediates- biradicals, enamines, carbenes, nitrenes, benzyne and their
reactions, energetics of organic reactions.
Alicyclic compounds —classification, synthesis of alicyclic compounds, physical and
chemical properties, Baeyer’s strain theory, strainless or puckered theory, relative
stability of chair and boat form, relative stability of cycloalkanes in terms of M.O. theory,
medium ring compounds, large ring compounds, natural compounds with large rings
(civetone and muscone)
Stereochemistry - Enantiomers, diastereomers, fischer projection formula, optical
isomerism in compounds containing no chiral carbon atom, racemic modification,
resolution of racemic modification, asymmetric synthesis, stereochemistry and reaction
mechanism, relative and absolute configuration, modern interpretation of geometrical
isomerism, interconversion of geometrical isomers, stereochemistry of cycloparaffins,
stereochemistry of nitrogen, phosphorous, sulphur and arsenic compounds.
Tautomerism- Classification, dyad system, triad system, ring chain tautomerism,
valence tautomerism.
Conformational analysis —Confonnations, conformations of ethane, substituted ethanes,
cyclohexane, substituted cyclohexanes, cyclohexene, cyclohexanone, fused ring
compounds, other ring systems, conformations and chemical reactivity of acyclic
compounds and cyclic compounds.
Pericyclic reactions -Mechanism and stereochemistry of pericyclic reactions, types of
pericyclic reactions (cycloadditions, electrocyclic reactions, sigmatropic rearrangements),
(4+2) cycloadditions, (2+2) cycloadditions, electrocyclic reactions, woodward hoffmann
rule and orbital symmetry, sigmatropic rearrangement
Non benzenoid aromatic system-Ferrocene, fulvene, tropylium cation, tropone and
tropolone, azulene, annulenes, heterocyclic compounds, sydnones.
Reading materials
1. A Concise Introduction to Organic Chemistry by A. Zlatkis. Publisher : McGraw-
Hill Companies.
2. A Guide Book to Mechanism in Organic Chemistry by P. Sykes. Publisher :
Longmans.
3. Advanced Organic Chemistry - Reactions, Mechanisms and Structure by J.
March. Publisher : McGraw Hill Text.
4. Introduction to Organic Chemistry by D.E. Applequist, C.H. Depuy and K.L.
Rinehart, Jr. Publisher : John Wiley and Sons Inc.
5. Organic Chemistry by F.A. Carey and R.J. Sundberg. Publisher : Plenum
Publishing Corporation.
6. Organic Chemistry by J. B. Hendrickson, S.H. Pine, D.J. Cram and G.S.
Hammond. Publisher : McGraw Hill.
7. Organic Chemistry by R.T. Morrison and R.N. Boyd. Publisher : Prentice Hall
College Division.
8. Organic Chemistry : The Basis of Life by B. Miller. Publisher : Addison-Wesley
Publishing Company.
9. Practical Organic Chemistry by F.G. Mann and B.C. Saunders. Publisher :
Longman.
10. Vogel’s Textbook of Practical Organic Chemistry by A.I. Vogel, B.S. Furniss,
and A.R. Tatchell. Publisher : Addison-Wesley Publishing Company.
B.E. (Bio-technology) I Year: II Semester
Examination Theory L T P
Paper IV BT 114 Mechanical Sciences 3 1 0
Applied Mechanics — basic laws: force, moment of a force, couple, equivalent force
system, equation of equilibrium, applications of structural mechanics, friction and its
applications
Simple stresses and strains — Description of tensile, comprehensive shear and volumetric stresses and strains, complementary shear stress, lateral strain and Poisson’s ratio
Bending moment and shear force diagrams — Cantilevers and simply supported beams carrying various types of loads
Theory of simple bending — Determination of bending stresses, deflection of beams
Torsion 1 Stresses and strains in pure torsion for solid and hollow circular shaft : power transmitted by shaft.
Combined stresses and strains : Principal stresses, strains, combined torsion, bending and
direct stresses, strains, combine torsion, bending and direct stresses.
Fluid mechanics — Fluid and flow, fluid properties, pressure variation in a static fluid,
hydrostatic forces on plane and curved surfaces, stability of submerged and floating
bodies. Properties of fluids, classification of fluids, forces on fluids. Normal forces on
fluids, forces on submerged bodies, hydrostatic forces on plane and curved surfaces.
General description of fluid motion, streamlines, continuity equation, particle
acceleration, velocity gradient, rotation and rate of strain.
Thermodynamics — Concepts of system, properties, equilibrium, zeroth law, heat and
work, first law of thermodynamics, nonflow and steady flow energy equations, second
law of thermodynamics, reversibility, entropy, properties of ideal gases, various
thermodynamic processes. Properties of air, water, vapour mixtures, introduction to
psychrometry.
Introduction of heat transfer modes, concept of driving potential, thermal resistance and overall heat transfer coefficient.
Reading materials
l. A Text Book of Fluid Mechanics and Hydraulic Machines (For Degree, U.P.S.C.,
A.M.I.E. Classes) by R.K. Bansal. Publisher 1 Laxmi Publications Pvt. Ltd.
2. Applied Mechanics by F.P. Beer and E.R. Johnston. Publisher: McGraw-Hill
Science/Engineering/Math.
3. Basic and Applied Thermodynamics by PK. Nag. Publisher : Tata McGraw Hill
Publishing Company.
4. Engineering Mechanics , Statics by I.H. Shames. Publisher : Pearson education.
5. Engineering Mechanics, Statics by J .L. Meriam. LG. Kraige and J. William III.
Publisher : John Wiley and Sons Inc.
6. Fundamentals of Fluid Mechanics by B.R. Munson, D.F. Young and T.H. Okiishi.
Publisher 2 John Wiley and Sons Inc.
7. Fundamentals of Thermodynamics by G. Van Wylen and R.E. Sonntag. Publisher
: John Wiley and Sons Inc.
8. Mechanics of Fluids by I.H. Shames. Publisher: McGraw-Hill
Science/Engineering/Math.
9. Thermodynamics : Principles Characterizing Physical and Chemical Processes
by J .Honig, M. Honig and M. Jurgen. Publisher : Academic Press.
B.E. (Bio-technology): I Year: II Semester
Examination Theory L T P
Paper V BT 115 Engineering Mathematics 3 1 0
Differential Equations: General linear differential equations with constant coefficients,
Operator D, Complementary function, particular integral, Wronskian, Simultaneous
linear differential equations, Solution of differential equations in power series, Frobenius method.
Fourier Series: Fourier Series, Euler’s Formula, Even and odd-functions, functions
having arbitrary periods, half range expansions, Harmonic Analysis
.
Laplace Transform: Laplace Transformation, Inverse Laplace Transformation,
Convolution Theorem, Application to Linear differential equations with constant
coefficient, Unit step fimction, Impulse function, Periodic function.
Functions of Complex Variable: Analytic Functions, Harmonic Conjugate, Conformal
Mapping, Cauchy’s Integral theorem, Cauchy’s Integral Formula, Residue Theorem,
Evaluation of real integrals.
Vector Analysis: The operators gradient, divergence and curl and their geometrical
significance, Integration of vectors, Work done in vector fields, Green’s, Stokes and
Gauss divergence theorem.
Partial Differential Equations: Linear Partial Differential Equations. Applications of
Partial Differential equations, Method of Separation of Variables, Heat equation, Wave Equation, Laplace Equation and their solutions.
Numerical Methods: Solution of system of Linear equations, Solution of Algebraic and
Transcendental Equations, Interpolation and Approximation, Numerical Integration,
Numerical Solutions to Differential Equations. Dynamics and initial value problems
Integrators - Euler method, Runga-Kutta, Verlet, Harmonic Oscillator, Monte Carlo
simulation on a 2D lattice: chain collapse and protein folding. Optimization- Steepest
Descent, Conjugate gradient, Discrete optimization by Monte Carlo: Design of an
optimal sequence
Reading materials
1. Advance Engineering Mathematics by E. Kreyszig. Publisher : John Wiley and
Sons Inc.
2. Calculus by G.B. Thomas and R.L. Finney. Publisher: Addison-Wesley
Publishing.
3. Elements of Partial Differential Equations by I.N. Sneddon.
4. Schaum's Outline of Fourier Analysis with Applications to Boundary Value
Problems by M.R. Spiegel. Publisher : McGraw Hill Trade.
5. Schaum's Outline of Laplace Transforms by M.R. Spiegel. Publisher : McGraw
Hill Trade.
B.E. (Bio-technology): I Year: II Semester
Examination Practical L T P
Paper I BT 116 Introduction to Biotechnology Lab. 0 0 3
(Practicals based on course work corresponding to BT 111)
1. Biotechnology lab. orientation and safety guidelines
2. Use of microscopes to examine various cell types, characteristics of cell structure
and function, a study of scale and number.
3. Create Three-dimensional model of DNA molecule using molecule building kit.
4. DNA Electrophoresis — submarine gel electrophoresis and visualization of bands.
5. Restriction analysis of DNA
6. Ligation of DNA to construct a recombinant molecule
7. Transformation and screening of recombinant colonies.
B.E. (Bio-technology): I Year: II Semester
Examination Practical L T P
Paper II BT 117 Physics II Lab.. 0 0 2
(Practicals based on course work corresponding to BT 112)
1. Measurement of Planck’s constant and work function.
2. Measurement of resistivity of a semi conductor using four probe method.
3. Wave length of laser light from the diffraction of pattem from a slit.
4. Diffraction of laser light from a plane grating.
5. Hall effect experiment.
6. P vs E plot for a dielectric.
7. B-H loop of a ferromagnetic material
8. GM tube characteristics
9. Statistical analysis of data ,13 -count using GM tube
10. Experiments with y- rays using Na-I detector.
B.E. (Bio-technology): I Year: II Semester
Examination Practical L T P
Paper III BT 118 Chemistry II Lab. 0 0 3
(Practicals based on course work corresponding to BT 113)
1. Qualitative organic analysis — Analysis of binary organic mixtures- Tests with the
mixture, Separation of the mixture, Purification of the separated compounds,
Identification of components.
2. Qualitative organic analysis - Element detection, Detection of functional groups,
Determination of melting and boiling points, Specific or confirmatory tests,
Preparation of suitable derivatives.
3. Quantitative organic analysis - Estimation of sulphur, nitrogen, halogens, aniline,
glycine, phenol, glucose, determination of molecular weight.
4. Chemical hydrolysis of a protein, carbohydrate, lipid and characterization of the
products.
B.E. (Bio-technology): I Year: II Semester
Examination Practical L T P
Paper IV BT 119 Mechanical Sciences Lab.. 0 0 2
(Practicals based on course work corresponding to BT 114)
1. To verify the law of moments by using bell crank lever.
2. To conduct experiment on simply supported beam for verification of law of
moments.
3. To verify the law of polygon of forces by using force table.
4. To find the coefficient of friction between glass and wood.
5. To determine the coefficient of discharge Cd, velocity Cv and contraction Cc of
various types of orifices, such as circular square, triangular of various dimensions.
6. To determine the discharge coefficient of various notches such as V-notch,
Rectangular notch, trapezoidal notch.
7. To verify the forces in shear legs by graphical method.
8. To study the laminar flow and plot the velocity distribution profile for laminar
flow in pipes.
9. To find the forces in various members of tmss.
10. To find friction factor for pipes of different diameters of same material.
ll. To calibrate Venturi meter by establishing the relationship between flow rate and
pressure differences and to find its coefficient of discharge.
